Carotti A - Search Results

1

Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors.

Ferri M, Liscio P, Carotti A, Asciutti S, Sardella R, Macchiarulo A, Camaioni E. Ferri M, et al. Among authors: carotti a. Eur J Med Chem. 2017 Dec 15;142:506-522. doi: 10.1016/j.ejmech.2017.09.030. Epub 2017 Oct 7. Eur J Med Chem. 2017. PMID: 29107427 Review.

2

Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA.

Pellicciari R, Venturoni F, Bellocchi D, Carotti A, Marinozzi M, Macchiarulo A, Amori L, Schwarcz R. Pellicciari R, et al. Among authors: carotti a. ChemMedChem. 2008 Aug;3(8):1199-202. doi: 10.1002/cmdc.200800109. ChemMedChem. 2008. PMID: 18537204 No abstract available.

3

Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition.

Macchiarulo A, Giacchè N, Carotti A, Baroni M, Cruciani G, Pellicciari R. Macchiarulo A, et al. Among authors: carotti a. J Chem Inf Model. 2008 Oct;48(10):1999-2009. doi: 10.1021/ci800146m. Epub 2008 Oct 1. J Chem Inf Model. 2008. PMID: 18826207

4

Targeting the conformational transitions of MDM2 and MDMX: insights into key residues affecting p53 recognition.

Carotti A, Macchiarulo A, Giacchè N, Pellicciari R. Carotti A, et al. Proteins. 2009 Nov 15;77(3):524-35. doi: 10.1002/prot.22464. Proteins. 2009. PMID: 19507240

5

Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: the round dance of kynurenine aminotransferase II.

Bellocchi D, Macchiarulo A, Carotti A, Pellicciari R. Bellocchi D, et al. Among authors: carotti a. Biochim Biophys Acta. 2009 Dec;1794(12):1802-12. doi: 10.1016/j.bbapap.2009.08.016. Epub 2009 Aug 26. Biochim Biophys Acta. 2009. PMID: 19715778

6

Molecular interaction fields and 3D-QSAR studies of p53-MDM2 inhibitors suggest additional features of ligand-target interaction.

Dezi C, Carotti A, Magnani M, Baroni M, Padova A, Cruciani G, Macchiarulo A, Pellicciari R. Dezi C, et al. Among authors: carotti a. J Chem Inf Model. 2010 Aug 23;50(8):1451-65. doi: 10.1021/ci100113p. J Chem Inf Model. 2010. PMID: 20726601

7

Extending SAR of bile acids as FXR ligands: discovery of 23-N-(carbocinnamyloxy)-3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-amine.

Gioiello A, Macchiarulo A, Carotti A, Filipponi P, Costantino G, Rizzo G, Adorini L, Pellicciari R. Gioiello A, et al. Among authors: carotti a. Bioorg Med Chem. 2011 Apr 15;19(8):2650-8. doi: 10.1016/j.bmc.2011.03.004. Epub 2011 Mar 10. Bioorg Med Chem. 2011. PMID: 21459580

8

Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists.

Marinozzi M, Carotti A, Sansone E, Macchiarulo A, Rosatelli E, Sardella R, Natalini B, Rizzo G, Adorini L, Passeri D, De Franco F, Pruzanski M, Pellicciari R. Marinozzi M, et al. Among authors: carotti a. Bioorg Med Chem. 2012 Jun 1;20(11):3429-45. doi: 10.1016/j.bmc.2012.04.021. Epub 2012 Apr 20. Bioorg Med Chem. 2012. PMID: 22564381

9

Chiral mobile phase in ligand-exchange chromatography of amino acids: exploring the copper(II) salt anion effect with a computational approach.

Sardella R, Macchiarulo A, Carotti A, Ianni F, Rubiño ME, Natalini B. Sardella R, et al. Among authors: carotti a. J Chromatogr A. 2012 Dec 21;1269:316-24. doi: 10.1016/j.chroma.2012.08.018. Epub 2012 Aug 16. J Chromatogr A. 2012. PMID: 22926052

10

Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: role of the chirality on the biological activity.

Marinozzi M, Carotti A, Sardella R, Buonerba F, Ianni F, Natalini B, Passeri D, Rizzo G, Pellicciari R. Marinozzi M, et al. Among authors: carotti a. Bioorg Med Chem. 2013 Jul 1;21(13):3780-9. doi: 10.1016/j.bmc.2013.04.038. Epub 2013 Apr 23. Bioorg Med Chem. 2013. PMID: 23684233

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