Thomé C - Search Results

1

Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders.

Beierfuß A, Dietrich H, Kremser C, Hunjadi M, Ritsch A, Rülicke T, Thomé C, Mern DS. Beierfuß A, et al. Among authors: thome c. PLoS One. 2017 Nov 3;12(11):e0187564. doi: 10.1371/journal.pone.0187564. eCollection 2017. PLoS One. 2017. PMID: 29099857 Free PMC article.

2

Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review.

Mern DS, Beierfuß A, Thomé C, Hegewald AA. Mern DS, et al. Among authors: thome c. J Tissue Eng Regen Med. 2014 Dec;8(12):925-36. doi: 10.1002/term.1583. Epub 2012 Aug 23. J Tissue Eng Regen Med. 2014. PMID: 22927290 Review.

3

Enhancing tissue repair in annulus fibrosus defects of the intervertebral disc: analysis of a bio-integrative annulus implant in an in-vivo ovine model.

Hegewald AA, Medved F, Feng D, Tsagogiorgas C, Beierfuß A, Schindler GA, Trunk M, Kaps C, Mern DS, Thomé C. Hegewald AA, et al. Among authors: thome c. J Tissue Eng Regen Med. 2015 Apr;9(4):405-14. doi: 10.1002/term.1831. Epub 2013 Nov 12. J Tissue Eng Regen Med. 2015. PMID: 24227682

4

A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential target proteins for gene therapeutic approaches.

Mern DS, Fontana J, Beierfuß A, Thomé C, Hegewald AA. Mern DS, et al. Among authors: thome c. PLoS One. 2013 Nov 21;8(11):e81467. doi: 10.1371/journal.pone.0081467. eCollection 2013. PLoS One. 2013. PMID: 24278441 Free PMC article.

5

Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseases.

Mern DS, Beierfuβ A, Fontana J, Thomé C, Hegewald AA. Mern DS, et al. Among authors: thome c. PLoS One. 2014 May 7;9(5):e96870. doi: 10.1371/journal.pone.0096870. eCollection 2014. PLoS One. 2014. PMID: 24804684 Free PMC article.

6

Regenerative and immunogenic characteristics of cultured nucleus pulposus cells from human cervical intervertebral discs.

Stich S, Stolk M, Girod PP, Thomé C, Sittinger M, Ringe J, Seifert M, Hegewald AA. Stich S, et al. Among authors: thome c. PLoS One. 2015 May 19;10(5):e0126954. doi: 10.1371/journal.pone.0126954. eCollection 2015. PLoS One. 2015. PMID: 25993467 Free PMC article.

7

Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders.

Mern DS, Thomé C. Mern DS, et al. Among authors: thome c. BMC Musculoskelet Disord. 2015 Nov 9;16:341. doi: 10.1186/s12891-015-0799-4. BMC Musculoskelet Disord. 2015. PMID: 26552484 Free PMC article.

8

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.

Mern DS, Tschugg A, Hartmann S, Thomé C. Mern DS, et al. Among authors: thome c. PLoS One. 2017 Feb 16;12(2):e0172181. doi: 10.1371/journal.pone.0172181. eCollection 2017. PLoS One. 2017. PMID: 28207788 Free PMC article.

9

APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix.

Beierfuß A, Hunjadi M, Ritsch A, Kremser C, Thomé C, Mern DS. Beierfuß A, et al. Among authors: thome c. PLoS One. 2019 Nov 21;14(11):e0225527. doi: 10.1371/journal.pone.0225527. eCollection 2019. PLoS One. 2019. PMID: 31751427 Free PMC article.

10

Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases.

Mern DS, Walsen T, Beierfuß A, Thomé C. Mern DS, et al. Among authors: thome c. Exp Biol Med (Maywood). 2021 Feb;246(4):483-512. doi: 10.1177/1535370220969123. Epub 2020 Nov 11. Exp Biol Med (Maywood). 2021. PMID: 33175609 Free PMC article. Review.

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