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Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules.
Hsieh CJ, Ferrie JJ, Xu K, Lee I, Graham TJA, Tu Z, Yu J, Dhavale D, Kotzbauer P, Petersson EJ, Mach RH. Hsieh CJ, et al. ACS Chem Neurosci. 2018 Nov 21;9(11):2521-2527. doi: 10.1021/acschemneuro.8b00177. Epub 2018 May 16. ACS Chem Neurosci. 2018. PMID: 29750499 Free PMC article.
Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery.
Pipal RW, Stout KT, Musacchio PZ, Ren S, Graham TJA, Verhoog S, Gantert L, Lohith TG, Schmitz A, Lee HS, Hesk D, Hostetler ED, Davies IW, MacMillan DWC. Pipal RW, et al. Nature. 2021 Jan;589(7843):542-547. doi: 10.1038/s41586-020-3015-0. Epub 2020 Nov 25. Nature. 2021. PMID: 33238289 Free PMC article.
PARP Targeted Alpha-Particle Therapy Enhances Response to PD-1 Immune-Checkpoint Blockade in a Syngeneic Mouse Model of Glioblastoma.
Dabagian H, Taghvaee T, Martorano P, Martinez D, Samanta M, Watkins CM, Chai R, Mansfield A, Graham TJ, Maris JM, Pryma DA, Mach RH, Makvandi M. Dabagian H, et al. Among authors: graham tj. ACS Pharmacol Transl Sci. 2021 Jan 26;4(1):344-351. doi: 10.1021/acsptsci.0c00206. eCollection 2021 Feb 12. ACS Pharmacol Transl Sci. 2021. PMID: 33615184 Free PMC article.
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. Among authors: graham tja. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366 Free PMC article.
60 results