Cairns J - Search Results

1

Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform.

Lanz HL, Saleh A, Kramer B, Cairns J, Ng CP, Yu J, Trietsch SJ, Hankemeier T, Joore J, Vulto P, Weinshilboum R, Wang L. Lanz HL, et al. Among authors: cairns j. BMC Cancer. 2017 Nov 2;17(1):709. doi: 10.1186/s12885-017-3709-3. BMC Cancer. 2017. PMID: 29096610 Free PMC article.

2

Anastrozole Regulates Fatty Acid Synthase in Breast Cancer.

Cairns J, Ingle JN, Kalari KR, Goetz MP, Weinshilboum RM, Gao H, Li H, Bari MG, Wang L. Cairns J, et al. Mol Cancer Ther. 2022 Jan;21(1):206-216. doi: 10.1158/1535-7163.MCT-21-0509. Epub 2021 Oct 19. Mol Cancer Ther. 2022. PMID: 34667110 Free PMC article.

3

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.

Cairns J, Ingle JN, Wickerham LD, Weinshilboum R, Liu M, Wang L. Cairns J, et al. PLoS Genet. 2017 Oct 2;13(10):e1007031. doi: 10.1371/journal.pgen.1007031. eCollection 2017 Oct. PLoS Genet. 2017. PMID: 28968398 Free PMC article.

4

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.

Cairns J, Ung CY, da Rocha EL, Zhang C, Correia C, Weinshilboum R, Wang L, Li H. Cairns J, et al. Sci Rep. 2016 Nov 14;6:37003. doi: 10.1038/srep37003. Sci Rep. 2016. PMID: 27841317 Free PMC article.

5

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer.

Athreya AP, Kalari KR, Cairns J, Gaglio AJ, Wills QF, Niu N, Weinshilboum R, Iyer RK, Wang L. Athreya AP, et al. Among authors: cairns j. Oncotarget. 2017 Apr 18;8(16):27199-27215. doi: 10.18632/oncotarget.16109. Oncotarget. 2017. PMID: 28423712 Free PMC article.

6

Computational discovery of transcription factors associated with drug response.

Hanson C, Cairns J, Wang L, Sinha S. Hanson C, et al. Among authors: cairns j. Pharmacogenomics J. 2016 Nov;16(6):573-582. doi: 10.1038/tpj.2015.74. Epub 2015 Oct 27. Pharmacogenomics J. 2016. PMID: 26503816 Free PMC article.

7

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.

Cairns J, Fridley BL, Jenkins GD, Zhuang Y, Yu J, Wang L. Cairns J, et al. EMBO Rep. 2018 Mar;19(3):e44767. doi: 10.15252/embr.201744767. Epub 2018 Jan 15. EMBO Rep. 2018. PMID: 29335246 Free PMC article.

8

Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor α.

Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Hoskin TL, Singh RJ, Desta Z, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, Haddad T, Goetz MP, Goodnature B, Cuellar ME, Walters MA, Correia C, Kaufmann SH, Weinshilboum RM, Wang L. Ingle JN, et al. Among authors: cairns j. Clin Cancer Res. 2020 Jun 15;26(12):2986-2996. doi: 10.1158/1078-0432.CCR-19-3091. Epub 2020 Feb 25. Clin Cancer Res. 2020. PMID: 32098767 Free PMC article.

9

Machine Learning Helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer.

Athreya AP, Gaglio AJ, Cairns J, Kalari KR, Weinshilboum RM, Wang L, Kalbarczyk ZT, Iyer RK. Athreya AP, et al. Among authors: cairns j. IEEE Trans Nanobioscience. 2018 Jul;17(3):251-259. doi: 10.1109/TNB.2018.2851997. Epub 2018 Jul 2. IEEE Trans Nanobioscience. 2018. PMID: 29994716 Free PMC article.

10

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Cairns J, Ingle JN, Kalari KR, Shepherd LE, Kubo M, Goetz MP, Weinshilboum RM, Wang L. Cairns J, et al. Breast Cancer Res. 2019 Apr 3;21(1):47. doi: 10.1186/s13058-019-1130-3. Breast Cancer Res. 2019. PMID: 30944027 Free PMC article.

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