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Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation.
Sula Karreci E, Eskandari SK, Dotiwala F, Routray SK, Kurdi AT, Assaker JP, Luckyanchykov P, Mihali AB, Maarouf O, Borges TJ, Alkhudhayri A, Patel KR, Radwan A, Ghobrial I, McGrath M, Chandraker A, Riella LV, Elyaman W, Abdi R, Lieberman J, Azzi J. Sula Karreci E, et al. Among authors: chandraker a. JCI Insight. 2017 Nov 2;2(21):e91599. doi: 10.1172/jci.insight.91599. JCI Insight. 2017. PMID: 29093262 Free PMC article.
The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo.
Yang J, Riella LV, Chock S, Liu T, Zhao X, Yuan X, Paterson AM, Watanabe T, Vanguri V, Yagita H, Azuma M, Blazar BR, Freeman GJ, Rodig SJ, Sharpe AH, Chandraker A, Sayegh MH. Yang J, et al. Among authors: chandraker a. J Immunol. 2011 Aug 1;187(3):1113-9. doi: 10.4049/jimmunol.1100056. Epub 2011 Jun 22. J Immunol. 2011. PMID: 21697455 Free PMC article.
Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model.
Riella LV, Liu T, Yang J, Chock S, Shimizu T, Mfarrej B, Batal I, Xiao X, Sayegh MH, Chandraker A. Riella LV, et al. Among authors: chandraker a. Am J Transplant. 2012 Apr;12(4):846-55. doi: 10.1111/j.1600-6143.2011.03929.x. Epub 2012 Feb 2. Am J Transplant. 2012. PMID: 22300534 Free article.
215 results