Perez-Lara A - Search Results

1

Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease.

Lüningschrör P, Binotti B, Dombert B, Heimann P, Perez-Lara A, Slotta C, Thau-Habermann N, R von Collenberg C, Karl F, Damme M, Horowitz A, Maystadt I, Füchtbauer A, Füchtbauer EM, Jablonka S, Blum R, Üçeyler N, Petri S, Kaltschmidt B, Jahn R, Kaltschmidt C, Sendtner M. Lüningschrör P, et al. Nat Commun. 2017 Oct 30;8(1):678. doi: 10.1038/s41467-017-00689-z. Nat Commun. 2017. PMID: 29084947 Free PMC article.

2

Control of membrane gaps by synaptotagmin-Ca2+ measured with a novel membrane distance ruler.

Lin CC, Seikowski J, Pérez-Lara A, Jahn R, Höbartner C, Walla PJ. Lin CC, et al. Nat Commun. 2014 Dec 15;5:5859. doi: 10.1038/ncomms6859. Nat Commun. 2014. PMID: 25500905 Free PMC article.

3

Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed.

Pérez-Lara Á, Jahn R. Pérez-Lara Á, et al. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):4837-8. doi: 10.1073/pnas.1504487112. Epub 2015 Apr 7. Proc Natl Acad Sci U S A. 2015. PMID: 25852145 Free PMC article. No abstract available.

4

Synaptotagmin-1 binds to PIP(2)-containing membrane but not to SNAREs at physiological ionic strength.

Park Y, Seo JB, Fraind A, Pérez-Lara A, Yavuz H, Han K, Jung SR, Kattan I, Walla PJ, Choi M, Cafiso DS, Koh DS, Jahn R. Park Y, et al. Nat Struct Mol Biol. 2015 Oct;22(10):815-23. doi: 10.1038/nsmb.3097. Epub 2015 Sep 21. Nat Struct Mol Biol. 2015. PMID: 26389740 Free PMC article.

5

PtdInsP₂ and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium.

Pérez-Lara Á, Thapa A, Nyenhuis SB, Nyenhuis DA, Halder P, Tietzel M, Tittmann K, Cafiso DS, Jahn R. Pérez-Lara Á, et al. Elife. 2016 Oct 28;5:e15886. doi: 10.7554/eLife.15886. Elife. 2016. PMID: 27791979 Free PMC article.

6

Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion.

Lakomek NA, Yavuz H, Jahn R, Pérez-Lara Á. Lakomek NA, et al. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8699-8708. doi: 10.1073/pnas.1813194116. Epub 2019 Apr 11. Proc Natl Acad Sci U S A. 2019. PMID: 30975750 Free PMC article.

7

Characterization of PROPPIN-Phosphoinositide Binding by Stopped-Flow Fluorescence Spectroscopy.

Pérez-Lara Á, Jahn R. Pérez-Lara Á, et al. Methods Mol Biol. 2021;2251:205-214. doi: 10.1007/978-1-0716-1142-5_15. Methods Mol Biol. 2021. PMID: 33481242

8

Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes.

Wittig S, Ganzella M, Barth M, Kostmann S, Riedel D, Pérez-Lara Á, Jahn R, Schmidt C. Wittig S, et al. Nat Commun. 2021 Feb 8;12(1):858. doi: 10.1038/s41467-021-21102-w. Nat Commun. 2021. PMID: 33558502 Free PMC article.

9

An overview of the synaptic vesicle lipid composition.

Binotti B, Jahn R, Pérez-Lara Á. Binotti B, et al. Arch Biochem Biophys. 2021 Sep 30;709:108966. doi: 10.1016/j.abb.2021.108966. Epub 2021 Jun 15. Arch Biochem Biophys. 2021. PMID: 34139199 Free article. Review.

10

Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P₂ Interaction in Constrained Geometries.

Dietz J, Oelkers M, Hubrich R, Pérez-Lara A, Jahn R, Steinem C, Janshoff A. Dietz J, et al. Among authors: perez lara a. Nano Lett. 2022 Feb 9;22(3):1449-1455. doi: 10.1021/acs.nanolett.1c02491. Epub 2021 Dec 2. Nano Lett. 2022. PMID: 34855407

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