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GA101 P329GLALA, a variant of obinutuzumab with abolished ADCC, ADCP and CDC function but retained cell death induction, is as efficient as rituximab in B-cell depletion and antitumor activity.
Herter S, Herting F, Muth G, van Puijenbroek E, Schlothauer T, Ferrara C, Brady K, Lang S, Bacac M, Mössner E, Umana P, Klein C. Herter S, et al. Among authors: brady k. Haematologica. 2018 Feb;103(2):e78-e81. doi: 10.3324/haematol.2017.178996. Epub 2017 Oct 27. Haematologica. 2018. PMID: 29079598 Free PMC article. No abstract available.
A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease.
Peterson LB, Bell CJM, Howlett SK, Pekalski ML, Brady K, Hinton H, Sauter D, Todd JA, Umana P, Ast O, Waldhauer I, Freimoser-Grundschober A, Moessner E, Klein C, Hosse RJ, Wicker LS. Peterson LB, et al. Among authors: brady k. J Autoimmun. 2018 Dec;95:1-14. doi: 10.1016/j.jaut.2018.10.017. Epub 2018 Nov 13. J Autoimmun. 2018. PMID: 30446251 Free PMC article.
Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans.
Grimm HP, Schumacher V, Schäfer M, Imhof-Jung S, Freskgård PO, Brady K, Hofmann C, Rüger P, Schlothauer T, Göpfert U, Hartl M, Rottach S, Zwick A, Seger S, Neff R, Niewoehner J, Janssen N. Grimm HP, et al. Among authors: brady k. MAbs. 2023 Jan-Dec;15(1):2261509. doi: 10.1080/19420862.2023.2261509. Epub 2023 Oct 12. MAbs. 2023. PMID: 37823690 Free PMC article.
From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides.
Braendli-Baiocco A, Festag M, Dumong Erichsen K, Persson R, Mihatsch MJ, Fisker N, Funk J, Mohr S, Constien R, Ploix C, Brady K, Berrera M, Altmann B, Lenz B, Albassam M, Schmitt G, Weiser T, Schuler F, Singer T, Tessier Y. Braendli-Baiocco A, et al. Among authors: brady k. Toxicol Sci. 2017 May 1;157(1):112-128. doi: 10.1093/toxsci/kfx025. Toxicol Sci. 2017. PMID: 28123102 Free PMC article.
Heart failure after left atrial appendage occlusion: Insights from the LAAOS III randomized trial.
Krisai P, Belley-Cote EP, McIntyre WF, Wong J, Tsiplova K, Brady K, Joseph P, Johansson I, Johnson L, Xing LY, Colli A, McGuinness S, Punjabi P, Reents W, Rega F, Budera P, Royse AG, Paparella D, Connolly S, Whitlock RP, Healey JS;  on behalf ofthe LAAOS III Investigators. Krisai P, et al. Among authors: brady k. Eur J Heart Fail. 2024 Nov 25. doi: 10.1002/ejhf.3536. Online ahead of print. Eur J Heart Fail. 2024. PMID: 39586754
Acceptability, Feasibility, and Appropriateness of the B-OK Bottles as an Implementation Strategy for Treatment Adherence Support by Medical Case Managers.
Richterman A, Klaiman T, Connelly R, Palma D, Ryu E, Schmucker L, Villarin K, Grosso G, Brady KA, Thirumurthy H, Buttenheim A. Richterman A, et al. Among authors: brady ka. Glob Implement Res Appl. 2024;4(4):433-445. doi: 10.1007/s43477-024-00135-5. Epub 2024 Sep 17. Glob Implement Res Appl. 2024. PMID: 39568617 Free PMC article.
Localized eruption of glabella and eyebrows.
Okoye C, Brady K, Shastry J. Okoye C, et al. Among authors: brady k. JAAD Case Rep. 2024 Aug 31;53:37-39. doi: 10.1016/j.jdcr.2024.08.008. eCollection 2024 Nov. JAAD Case Rep. 2024. PMID: 39430639 Free PMC article. No abstract available.
1,126 results