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Page 1
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.
Lima TI, Laurila PP, Wohlwend M, Morel JD, Goeminne LJE, Li H, Romani M, Li X, Oh CM, Park D, Rodríguez-López S, Ivanisevic J, Gallart-Ayala H, Crisol B, Delort F, Batonnet-Pichon S, Silveira LR, Sankabattula Pavani Veera Venkata L, Padala AK, Jain S, Auwerx J. Lima TI, et al. Sci Transl Med. 2023 May 17;15(696):eade6509. doi: 10.1126/scitranslmed.ade6509. Epub 2023 May 17. Sci Transl Med. 2023. PMID: 37196064
Exercise increases Rho-kinase activity and insulin signaling in skeletal muscle.
Muñoz VR, Gaspar RC, Kuga GK, da Rocha AL, Crisol BM, Botezelli JD, Baptista IL, Mekary RA, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Pauli JR. Muñoz VR, et al. Among authors: crisol bm. J Cell Physiol. 2018 Jun;233(6):4791-4800. doi: 10.1002/jcp.26278. Epub 2018 Jan 15. J Cell Physiol. 2018. PMID: 29219181
Nicotinamide riboside induces a thermogenic response in lean mice.
Crisol BM, Veiga CB, Lenhare L, Braga RR, Silva VRR, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER. Crisol BM, et al. Life Sci. 2018 Oct 15;211:1-7. doi: 10.1016/j.lfs.2018.09.015. Epub 2018 Sep 6. Life Sci. 2018. PMID: 30195617
Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice.
Gaspar RC, Muñoz VR, Kuga GK, Nakandakari SCBR, Crisol BM, Lenhare L, Breda L, Botezelli JD, Sant'Ana MR, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Pauli JR. Gaspar RC, et al. Among authors: crisol bm. Eur J Neurosci. 2019 Oct;50(7):3181-3190. doi: 10.1111/ejn.14490. Epub 2019 Jul 8. Eur J Neurosci. 2019. PMID: 31206806
NAD+ precursor increases aerobic performance in mice.
Crisol BM, Veiga CB, Braga RR, Lenhare L, Baptista IL, Gaspar RC, Muñoz VR, Cordeiro AV, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER. Crisol BM, et al. Eur J Nutr. 2020 Sep;59(6):2427-2437. doi: 10.1007/s00394-019-02089-z. Epub 2019 Sep 7. Eur J Nutr. 2020. PMID: 31494696
20 results