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A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice.
Jeong HW, Lee JW, Kim WS, Choe SS, Shin HJ, Lee GY, Shin D, Lee JH, Choi EB, Lee HK, Yon GH, Cho B, Kim HR, Choi SH, Chung YS, Park SB, Chung H, Ro S, Kim JB. Jeong HW, et al. Among authors: lee jw, lee jh, lee hk, lee gy. Mol Pharmacol. 2010 Nov;78(5):877-85. doi: 10.1124/mol.110.065748. Epub 2010 Aug 19. Mol Pharmacol. 2010. PMID: 20724462
A newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gamma.
Jeong HW, Lee JW, Kim WS, Choe SS, Kim KH, Park HS, Shin HJ, Lee GY, Shin D, Lee H, Lee JH, Choi EB, Lee HK, Chung H, Park SB, Park KS, Kim HS, Ro S, Kim JB. Jeong HW, et al. Among authors: lee h, lee jw, lee jh, lee hk, lee gy. Diabetes. 2011 Feb;60(2):496-506. doi: 10.2337/db09-1145. Diabetes. 2011. PMID: 21270261 Free PMC article.
G6PD up-regulation promotes pancreatic beta-cell dysfunction.
Lee JW, Choi AH, Ham M, Kim JW, Choe SS, Park J, Lee GY, Yoon KH, Kim JB. Lee JW, et al. Among authors: lee gy. Endocrinology. 2011 Mar;152(3):793-803. doi: 10.1210/en.2010-0606. Epub 2011 Jan 19. Endocrinology. 2011. PMID: 21248143
900 results