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Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.
Kuethe JT, Lee J, Thaisrivongs D, Yasuda N, Pollack SR, Leone J, DaSilva J, Biba M, Tsay FR, Regalado EL, Qi J, Li H, Poggetto GD, Cohen R. Kuethe JT, et al. Among authors: qi j. Org Lett. 2023 Jul 14;25(27):5001-5005. doi: 10.1021/acs.orglett.3c01635. Epub 2023 Jun 29. Org Lett. 2023. PMID: 37382389
Highly Diastereoselective Access to Densely Functionalized Piperidine Cores of Influenza Endonuclease Inhibitors via a Metal-Free SN1 Approach.
Zhang Y, Sun C, Guo L, Zhao K, Bennett F, Lam YH, Gao Q, Ruhl KE, Pirnot MT, Emmert MH, Hollenstein K, Eddins MJ, Su HP, Shao G, Song C, Lo MM, Peng F, Qi J, Crowley BM, McCauley JA, Price IR. Zhang Y, et al. Among authors: qi j. J Org Chem. 2025 Jan 2. doi: 10.1021/acs.joc.4c02379. Online ahead of print. J Org Chem. 2025. PMID: 39745425
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.
Li D, Sloman DL, Achab A, Zhou H, McGowan MA, White C, Gibeau C, Zhang H, Pu Q, Bharathan I, Hopkins B, Liu K, Ferguson H, Fradera X, Lesburg CA, Martinot TA, Qi J, Song ZJ, Yin J, Zhang H, Song L, Wan B, DAddio S, Solban N, Miller JR, Zamlynny B, Bass A, Freeland E, Ykoruk B, Hilliard C, Ferraro J, Zhai J, Knemeyer I, Otte KM, Vincent S, Sciammetta N, Pasternak A, Bennett DJ, Han Y. Li D, et al. Among authors: qi j. J Med Chem. 2022 Apr 28;65(8):6001-6016. doi: 10.1021/acs.jmedchem.1c01670. Epub 2022 Mar 3. J Med Chem. 2022. PMID: 35239336
Biomarkers.
Le LNN, Fletcher E, Qi J, Fan AP. Le LNN, et al. Among authors: qi j. Alzheimers Dement. 2024 Dec;20 Suppl 2:e089483. doi: 10.1002/alz.089483. Alzheimers Dement. 2024. PMID: 39784175
7,635 results