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The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.
Herschhorn A, Gu C, Moraca F, Ma X, Farrell M, Smith AB 3rd, Pancera M, Kwong PD, Schön A, Freire E, Abrams C, Blanchard SC, Mothes W, Sodroski JG. Herschhorn A, et al. Among authors: mothes w. Nat Commun. 2017 Oct 19;8(1):1049. doi: 10.1038/s41467-017-01119-w. Nat Commun. 2017. PMID: 29051495 Free PMC article.
Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models.
Lorenzo MM, Marín-López A, Chiem K, Jimenez-Cabello L, Ullah I, Utrilla-Trigo S, Calvo-Pinilla E, Lorenzo G, Moreno S, Ye C, Park JG, Matía A, Brun A, Sánchez-Puig JM, Nogales A, Mothes W, Uchil PD, Kumar P, Ortego J, Fikrig E, Martinez-Sobrido L, Blasco R. Lorenzo MM, et al. Among authors: mothes w. Vaccines (Basel). 2023 May 21;11(5):1006. doi: 10.3390/vaccines11051006. Vaccines (Basel). 2023. PMID: 37243110 Free PMC article.
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy.
Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Ullah I, et al. Among authors: mothes w. bioRxiv [Preprint]. 2021 Jun 28:2021.03.22.436337. doi: 10.1101/2021.03.22.436337. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2143-2158.e15. doi: 10.1016/j.immuni.2021.08.015 PMID: 33791699 Free PMC article. Updated. Preprint.
The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice.
Ullah I, Beaudoin-Bussières G, Symmes K, Cloutier M, Ducas E, Tauzin A, Laumaea A, Grunst MW, Dionne K, Richard J, Bégin P, Mothes W, Kumar P, Bazin R, Finzi A, Uchil PD. Ullah I, et al. Among authors: mothes w. Cell Rep Med. 2023 Jan 17;4(1):100893. doi: 10.1016/j.xcrm.2022.100893. Epub 2022 Dec 29. Cell Rep Med. 2023. PMID: 36584683 Free PMC article.
In vivo imaging of virological synapses.
Sewald X, Gonzalez DG, Haberman AM, Mothes W. Sewald X, et al. Among authors: mothes w. Nat Commun. 2012;3:1320. doi: 10.1038/ncomms2338. Nat Commun. 2012. PMID: 23271654 Free PMC article.
The HIV-1 Env trimer in HD.
Munro JB, Mothes W. Munro JB, et al. Among authors: mothes w. Structure. 2014 Jul 8;22(7):935-6. doi: 10.1016/j.str.2014.06.004. Structure. 2014. PMID: 25007222 Free PMC article.
Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, Tumba N, Yang Y, Zhang B, Cohen MS, Haynes BF, Mascola JR, Morris L, Munro JB, Blanchard SC, Mothes W, Connors M, Kwong PD. Pancera M, et al. Among authors: mothes w. Nature. 2014 Oct 23;514(7523):455-61. doi: 10.1038/nature13808. Epub 2014 Oct 8. Nature. 2014. PMID: 25296255 Free PMC article.
148 results