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Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D. Turnbull AP, et al. Among authors: evans nj. Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18. Nature. 2017. PMID: 29045389 Free PMC article.
Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.
Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, Degorce SL, Donald C, Evans NJ, Groombridge S, Hopcroft P, Jones NP, Kettle JG, Lamont S, Lewis HJ, MacFaull P, McLoughlin SB, Rigoreau LJ, Smith JM, St-Gallay S, Stock JK, Turnbull AP, Wheatley ER, Winter J, Wingfield J. Boyd S, et al. Among authors: evans nj. J Med Chem. 2015 Apr 23;58(8):3611-25. doi: 10.1021/acs.jmedchem.5b00352. Epub 2015 Apr 13. J Med Chem. 2015. PMID: 25849762
A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors.
St-Gallay SA, Bennett N, Critchlow SE, Curtis N, Davies G, Debreczeni J, Evans N, Hardern I, Holdgate G, Jones NP, Leach L, Maman S, McLoughlin S, Preston M, Rigoreau L, Thomas A, Turnbull AP, Walker G, Walsh J, Ward RA, Wheatley E, Winter-Holt J. St-Gallay SA, et al. SLAS Discov. 2018 Jan;23(1):11-22. doi: 10.1177/2472555217732289. Epub 2017 Sep 25. SLAS Discov. 2018. PMID: 28945981 Free article.
Nucleophilicity at copper(-I) in a compound with a Cu-Mg bond.
Jackson RA, Evans NJ, Babula DJ, Horsley Downie TM, Charman RSC, Neale SE, Mahon MF, Liptrot DJ. Jackson RA, et al. Among authors: evans nj. Nat Commun. 2025 Jan 28;16(1):1101. doi: 10.1038/s41467-025-56544-z. Nat Commun. 2025. PMID: 39875432
A crustal Pb isotope map of southeastern Australia.
Liebmann J, Ware B, Mole DR, Kirkland CL, Fraser G, Waltenberg K, Bodorkos S, Huston DL, Evans NJ, McDonald BJ, Rankenburg K, Datta P, Tessalina S. Liebmann J, et al. Among authors: evans nj. Sci Data. 2024 Nov 12;11(1):1222. doi: 10.1038/s41597-024-03996-5. Sci Data. 2024. PMID: 39532888 Free PMC article.
Beyond discrete-choice options.
Rasanan AHH, Evans NJ, Fontanesi L, Manning C, Huang-Pollock C, Matzke D, Heathcote A, Rieskamp J, Speekenbrink M, Frank MJ, Palminteri S, Lucas CG, Busemeyer JR, Ratcliff R, Rad JA. Rasanan AHH, et al. Among authors: evans nj. Trends Cogn Sci. 2024 Sep;28(9):857-870. doi: 10.1016/j.tics.2024.07.004. Epub 2024 Aug 12. Trends Cogn Sci. 2024. PMID: 39138030 Free article. Review.
A billion-year shift in the formation of Earth's largest ore deposits.
Courtney-Davies L, Fiorentini M, Dalstra H, Hagemann S, Ramanaidou E, Danišik M, Evans NJ, Rankenburg K, McInnes BIA. Courtney-Davies L, et al. Among authors: evans nj. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2405741121. doi: 10.1073/pnas.2405741121. Epub 2024 Jul 23. Proc Natl Acad Sci U S A. 2024. PMID: 39042687 Free PMC article.
187 results