Ruddraraju K - Search Results

1

Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity.

Korasick DA, Wyatt JW, Luo M, Laciak AR, Ruddraraju K, Gates KS, Henzl MT, Tanner JJ. Korasick DA, et al. Among authors: ruddraraju k. Biochemistry. 2017 Nov 7;56(44):5910-5919. doi: 10.1021/acs.biochem.7b00803. Biochemistry. 2017. PMID: 29045138 Free PMC article.

2

Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) by an Inhibitor-Electrophile Conjugate.

Punthasee P, Laciak AR, Cummings AH, Ruddraraju KV, Lewis SM, Hillebrand R, Singh H, Tanner JJ, Gates KS. Punthasee P, et al. Among authors: ruddraraju kv. Biochemistry. 2017 Apr 11;56(14):2051-2060. doi: 10.1021/acs.biochem.7b00151. Epub 2017 Apr 3. Biochemistry. 2017. PMID: 28345882

3

Sulfone-stabilized carbanions for the reversible covalent capture of a posttranslationally-generated cysteine oxoform found in protein tyrosine phosphatase 1B (PTP1B).

Parsons ZD, Ruddraraju KV, Santo N, Gates KS. Parsons ZD, et al. Among authors: ruddraraju kv. Bioorg Med Chem. 2016 Jun 15;24(12):2631-40. doi: 10.1016/j.bmc.2016.03.054. Epub 2016 Apr 8. Bioorg Med Chem. 2016. PMID: 27132865

4

Crystal structure of a nucleoside model for the inter-strand cross-link formed by the reaction of 2'-de-oxy-guanosine and an abasic site in duplex DNA.

Catalano MJ, Ruddraraju KV, Barnes CL, Gates KS. Catalano MJ, et al. Among authors: ruddraraju kv. Acta Crystallogr E Crystallogr Commun. 2016 Apr 5;72(Pt 5):624-7. doi: 10.1107/S205698901600517X. eCollection 2016 May 1. Acta Crystallogr E Crystallogr Commun. 2016. PMID: 27308004 Free PMC article.

5

Crystal structure of 5-{4'-[(2-{2-[2-(2-ammonio-eth-oxy)eth-oxy]eth-oxy}eth-yl)carbamo-yl]-4-meth-oxy-[1,1'-biphen-yl]-3-yl}-3-oxo-1,2,5-thia-diazo-lidin-2-ide 1,1-dioxide: a potential inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B).

Ruddraraju KV, Hillebrand R, Barnes CL, Gates KS. Ruddraraju KV, et al. Acta Crystallogr E Crystallogr Commun. 2015 Mar 4;71(Pt 4):336-8. doi: 10.1107/S2056989015003850. eCollection 2015 Apr 1. Acta Crystallogr E Crystallogr Commun. 2015. PMID: 26029383 Free PMC article.

6

Crystal structure of methyl (S)-2-{(R)-4-[(tert-but-oxy-carbon-yl)amino]-3-oxo-1,2-thia-zolidin-2-yl}-3-methyl-butano-ate: a chemical model for oxidized protein tyrosine phosphatase 1B (PTP1B).

Ruddraraju KV, Hillebrand R, Barnes CL, Gates KS. Ruddraraju KV, et al. Acta Crystallogr E Crystallogr Commun. 2015 Jun 3;71(Pt 7):741-3. doi: 10.1107/S2056989015010051. eCollection 2015 Jul 1. Acta Crystallogr E Crystallogr Commun. 2015. PMID: 26279856 Free PMC article.

7

Reactions of 1,3-Diketones with a Dipeptide Isothiazolidin-3-one: Toward Agents That Covalently Capture Oxidized Protein Tyrosine Phosphatase 1B.

Ruddraraju KV, Parsons ZD, Llufrio EM, Frost NL, Gates KS. Ruddraraju KV, et al. J Org Chem. 2015 Dec 18;80(24):12015-26. doi: 10.1021/acs.joc.5b01949. Epub 2015 Nov 23. J Org Chem. 2015. PMID: 26517018

8

Correction to "Allylation and Alkylation of Biologically Relevant Nucleophiles by Diallyl Sulfides".

Ruddraraju KV, Parsons ZD, Lewis CD, Gates KS. Ruddraraju KV, et al. J Org Chem. 2017 Feb 17;82(4):2306. doi: 10.1021/acs.joc.7b00246. Epub 2017 Feb 7. J Org Chem. 2017. PMID: 28170252 No abstract available.

9

Highly Potent and Selective N-Aryl Oxamic Acid-Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B.

Ruddraraju KV, Aggarwal D, Niu C, Baker EA, Zhang RY, Wu L, Zhang ZY. Ruddraraju KV, et al. J Med Chem. 2020 Sep 10;63(17):9212-9227. doi: 10.1021/acs.jmedchem.0c00302. Epub 2020 Aug 21. J Med Chem. 2020. PMID: 32787087 Free PMC article.

10

Covalent inhibition of protein tyrosine phosphatases.

Ruddraraju KV, Zhang ZY. Ruddraraju KV, et al. Mol Biosyst. 2017 Jun 27;13(7):1257-1279. doi: 10.1039/c7mb00151g. Mol Biosyst. 2017. PMID: 28534914 Free PMC article. Review.

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