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Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging.
Wittköpper K, Fabritz L, Neef S, Ort KR, Grefe C, Unsöld B, Kirchhof P, Maier LS, Hasenfuss G, Dobrev D, Eschenhagen T, El-Armouche A. Wittköpper K, et al. Among authors: maier ls. J Clin Invest. 2010 Feb;120(2):617-26. doi: 10.1172/JCI40545. Epub 2010 Jan 11. J Clin Invest. 2010. PMID: 20071777 Free PMC article.
Unfavourable consequences of chronic cardiac HIF-1α stabilization.
Hölscher M, Schäfer K, Krull S, Farhat K, Hesse A, Silter M, Lin Y, Pichler BJ, Thistlethwaite P, El-Armouche A, Maier LS, Katschinski DM, Zieseniss A. Hölscher M, et al. Among authors: maier ls. Cardiovasc Res. 2012 Apr 1;94(1):77-86. doi: 10.1093/cvr/cvs014. Epub 2012 Jan 18. Cardiovasc Res. 2012. PMID: 22258630
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A. Mehel H, et al. Among authors: maier ls. J Am Coll Cardiol. 2013 Oct 22;62(17):1596-606. doi: 10.1016/j.jacc.2013.05.057. Epub 2013 Jun 26. J Am Coll Cardiol. 2013. PMID: 23810893 Free article.
Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.
Purohit A, Rokita AG, Guan X, Chen B, Koval OM, Voigt N, Neef S, Sowa T, Gao Z, Luczak ED, Stefansdottir H, Behunin AC, Li N, El-Accaoui RN, Yang B, Swaminathan PD, Weiss RM, Wehrens XH, Song LS, Dobrev D, Maier LS, Anderson ME. Purohit A, et al. Among authors: maier ls. Circulation. 2013 Oct 15;128(16):1748-57. doi: 10.1161/CIRCULATIONAHA.113.003313. Epub 2013 Sep 12. Circulation. 2013. PMID: 24030498 Free PMC article.
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.
Unsöld B, Kaul A, Sbroggiò M, Schubert C, Regitz-Zagrosek V, Brancaccio M, Damilano F, Hirsch E, Van Bilsen M, Munts C, Sipido K, Bito V, Detre E, Wagner NM, Schäfer K, Seidler T, Vogt J, Neef S, Bleckmann A, Maier LS, Balligand JL, Bouzin C, Ventura-Clapier R, Garnier A, Eschenhagen T, El-Armouche A, Knöll R, Tarone G, Hasenfuß G. Unsöld B, et al. Among authors: maier ls. Cardiovasc Res. 2014 Jan 1;101(1):97-107. doi: 10.1093/cvr/cvt235. Epub 2013 Oct 15. Cardiovasc Res. 2014. PMID: 24130190 Free article.
Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy.
Kreusser MM, Lehmann LH, Keranov S, Hoting MO, Oehl U, Kohlhaas M, Reil JC, Neumann K, Schneider MD, Hill JA, Dobrev D, Maack C, Maier LS, Gröne HJ, Katus HA, Olson EN, Backs J. Kreusser MM, et al. Among authors: maier ls. Circulation. 2014 Oct 7;130(15):1262-73. doi: 10.1161/CIRCULATIONAHA.114.006185. Epub 2014 Aug 14. Circulation. 2014. PMID: 25124496 Free PMC article.
Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII.
Fischer TH, Herting J, Mason FE, Hartmann N, Watanabe S, Nikolaev VO, Sprenger JU, Fan P, Yao L, Popov AF, Danner BC, Schöndube F, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S. Fischer TH, et al. Among authors: maier ls. Cardiovasc Res. 2015 Jul 1;107(1):184-96. doi: 10.1093/cvr/cvv153. Epub 2015 May 18. Cardiovasc Res. 2015. PMID: 25990311 Free PMC article.
427 results