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484 results

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Safety and efficacy of mitapivat in sickle cell disease (RISE UP): results from the phase 2 portion of a global, double-blind, randomised, placebo-controlled trial.
Idowu M, Otieno L, Dumitriu B, Lobo CLC, Thein SL, Andemariam B, Nnodu OE, Inati A, Glaros AK, Bartolucci P, Colombatti R, Taher AT, Abboud MR, Darbari D, Ataga KI, Antmen AB, Kuo KHM, de Souza Medina S, Oluyadi A, Iyer V, Morris S, Yates AM, Shao H, Patil S, Urbstonaitis R, Zaidi AU, Gheuens S, Smith WR. Idowu M, et al. Among authors: thein sl. Lancet Haematol. 2025 Jan;12(1):e35-e44. doi: 10.1016/S2352-3026(24)00319-3. Epub 2024 Dec 4. Lancet Haematol. 2025. PMID: 39644907 Clinical Trial.
A survey of gastrointestinal helminth infestation in smallholder backyard pigs and the first molecular identification of the two zoonotic helminths Ascaris suum and Trichuris suis in Myanmar.
Bawm S, Htun LL, Chel HM, Khaing Y, Hmoon MM, Thein SS, Win SY, Soe NC, Thaw YN, Hayashi N, Win MM, Nonaka N, Katakura K, Nakao R. Bawm S, et al. Among authors: thein ss. BMC Vet Res. 2024 Apr 6;20(1):139. doi: 10.1186/s12917-024-03998-w. BMC Vet Res. 2024. PMID: 38582856 Free PMC article.
Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease.
D'Alessandro A, Le K, Lundt M, Li Q, Dunkelberger EB, Cellmer T, Worth AJ, Patil S, Huston C, Grier A, Dzieciatkowska M, Stephenson D, Eaton WA, Thein SL. D'Alessandro A, et al. Among authors: thein sl. Haematologica. 2024 Aug 1;109(8):2639-2652. doi: 10.3324/haematol.2023.284831. Haematologica. 2024. PMID: 38450513 Free PMC article. Clinical Trial.
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation.
Leonard AK, Furstenau D, Inam Z, Luckett C, Chu R, Demirci S, Essawi K, Gudmundsdottir B, Hinds M, DiNicola J, Li Q, Eaton WA, Cellmer T, Wang X, Thein SL, Macari ER, VanNest S, Hsieh MM, Bonner M, Pierciey FJ, Tisdale JF. Leonard AK, et al. Among authors: thein sl. Blood Adv. 2024 Apr 9;8(7):1806-1816. doi: 10.1182/bloodadvances.2023011397. Blood Adv. 2024. PMID: 38181784 Free PMC article. Clinical Trial.
484 results