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Page 1
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. Swanson L, et al. Among authors: pranadinata rf. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020 Oct 14. Proc Natl Acad Sci U S A. 2020. PMID: 33055214 Free PMC article.
E-cigarettes compromise the gut barrier and trigger inflammation.
Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S. Sharma A, et al. Among authors: pranadinata rf. iScience. 2021 Jan 6;24(2):102035. doi: 10.1016/j.isci.2021.102035. eCollection 2021 Feb 19. iScience. 2021. PMID: 33537654 Free PMC article.
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Ambrus-Aikelin G, Takeda K, Joetham A, Lazic M, Povero D, Santini AM, Pranadinata R, Johnson CD, McGeough MD, Beasley FC, Stansfield R, McBride C, Trzoss L, Hoffman HM, Feldstein AE, Stafford JA, Veal JM, Bain G, Gelfand EW. Ambrus-Aikelin G, et al. Sci Rep. 2023 Aug 19;13(1):13524. doi: 10.1038/s41598-023-39805-z. Sci Rep. 2023. PMID: 37598239 Free PMC article.
A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics.
Tindle C, Fonseca AG, Taheri S, Katkar GD, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. Tindle C, et al. Among authors: pranadinata rf. Cell Rep Med. 2024 Oct 15;5(10):101748. doi: 10.1016/j.xcrm.2024.101748. Epub 2024 Sep 26. Cell Rep Med. 2024. PMID: 39332415 Free PMC article.
Molecular Signatures for Microbe-Associated Colorectal Cancers.
Sayed IM, Vo DT, Alcantara J, Inouye KM, Pranadinata RF, Luo L, Boland CR, Goyal NP, Kuo DJ, Huang SC, Sahoo D, Ghosh P, Das S. Sayed IM, et al. Among authors: pranadinata rf. bioRxiv [Preprint]. 2024 May 27:2024.05.26.595902. doi: 10.1101/2024.05.26.595902. bioRxiv. 2024. PMID: 38853996 Free PMC article. Preprint.
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
Povero D, Lazic M, McBride C, Ambrus-Aikelin G, Stansfield R, Johnson CD, Santini AM, Pranadinata RF, McGeough MD, Stafford JA, Hoffman HM, Feldstein AE, Veal JM, Bain G. Povero D, et al. Among authors: pranadinata rf. J Pharmacol Exp Ther. 2023 Aug;386(2):242-258. doi: 10.1124/jpet.123.001639. Epub 2023 Jun 12. J Pharmacol Exp Ther. 2023. PMID: 37308266
A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics.
Tindle C, Katkar GD, Fonseca AG, Taheri S, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. Tindle C, et al. Among authors: pranadinata rf. bioRxiv [Preprint]. 2023 Mar 13:2023.03.11.532245. doi: 10.1101/2023.03.11.532245. bioRxiv. 2023. Update in: Cell Rep Med. 2024 Oct 15;5(10):101748. doi: 10.1016/j.xcrm.2024.101748 PMID: 36993763 Free PMC article. Updated. Preprint.