Leong N - Search Results

1

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration.

Dong YD, Tchung E, Nowell C, Kaga S, Leong N, Mehta D, Kaminskas LM, Boyd BJ. Dong YD, et al. Among authors: leong n. J Liposome Res. 2019 Mar;29(1):1-9. doi: 10.1080/08982104.2017.1391285. Epub 2017 Nov 20. J Liposome Res. 2019. PMID: 29020849

2

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker.

Mehta D, Leong N, McLeod VM, Kelly BD, Pathak R, Owen DJ, Porter CJH, Kaminskas LM. Mehta D, et al. Among authors: leong n. Mol Pharm. 2018 Oct 1;15(10):4568-4576. doi: 10.1021/acs.molpharmaceut.8b00581. Epub 2018 Sep 13. Mol Pharm. 2018. PMID: 30107748

3

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats.

Leong NJ, Mehta D, McLeod VM, Kelly BD, Pathak R, Owen DJ, Porter CJH, Kaminskas LM. Leong NJ, et al. J Pharm Sci. 2018 Sep;107(9):2509-2513. doi: 10.1016/j.xphs.2018.05.013. Epub 2018 May 29. J Pharm Sci. 2018. PMID: 29852134

4

An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration.

Chan LJ, Feeney OM, Leong NJ, McLeod VM, Porter CJH, Williams CC, Kaminskas LM. Chan LJ, et al. Biomacromolecules. 2017 Sep 11;18(9):2866-2875. doi: 10.1021/acs.biomac.7b00794. Epub 2017 Aug 11. Biomacromolecules. 2017. PMID: 28731677

5

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats.

Kaminskas LM, Williams CC, Leong NJ, Chan LJ, Butcher NJ, Feeney OM, Porter CJH, Tyssen D, Tachedjian G, Ascher DB. Kaminskas LM, et al. Eur J Pharm Biopharm. 2019 Apr;137:218-226. doi: 10.1016/j.ejpb.2019.03.008. Epub 2019 Mar 6. Eur J Pharm Biopharm. 2019. PMID: 30851352

6

Aerosol Pirfenidone Pharmacokinetics after Inhaled Delivery in Sheep: a Viable Approach to Treating Idiopathic Pulmonary Fibrosis.

Kaminskas LM, Landersdorfer CB, Bischof RJ, Leong N, Ibrahim J, Davies AN, Pham S, Beck S, Montgomery AB, Surber MW. Kaminskas LM, et al. Among authors: leong n. Pharm Res. 2019 Dec 10;37(1):3. doi: 10.1007/s11095-019-2732-2. Pharm Res. 2019. PMID: 31823096

7

Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.

Kochappan R, Cao E, Han S, Hu L, Quach T, Senyschyn D, Ferreira VI, Lee G, Leong N, Sharma G, Lim SF, Nowell CJ, Chen Z, von Andrian UH, Bonner D, Mintern JD, Simpson JS, Trevaskis NL, Porter CJH. Kochappan R, et al. Among authors: leong n. J Control Release. 2021 Apr 10;332:636-651. doi: 10.1016/j.jconrel.2021.02.008. Epub 2021 Feb 17. J Control Release. 2021. PMID: 33609620 Free article.

8

The effect of intravenous sulfobutylether7 -β-cyclodextrin on the pharmacokinetics of a series of adamantane-containing compounds.

Leong NJ, Prankerd RJ, Shackleford DM, Mcintosh MP. Leong NJ, et al. J Pharm Sci. 2015 Apr;104(4):1492-8. doi: 10.1002/jps.24331. Epub 2015 Jan 8. J Pharm Sci. 2015. PMID: 25573540

9

Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids.

Lai A, Leong N, Zheng D, Ford L, Nguyen TH, Williams HD, Benameur H, Scammells PJ, Porter CJH. Lai A, et al. Among authors: leong n. Pharm Res. 2022 Oct;39(10):2405-2419. doi: 10.1007/s11095-022-03305-y. Epub 2022 Jun 3. Pharm Res. 2022. PMID: 35661084 Free PMC article.

10

Evaluation of the impact of sulfobutylether7 -β-cyclodextrin on the liquid chromatography-mass spectrometry analysis of biological samples arising from in vivo pharmacokinetic studies.

Leong NJ, Prankerd RJ, Shackleford DM, Mcintosh MP. Leong NJ, et al. J Pharm Sci. 2015 Apr;104(4):1561-2. doi: 10.1002/jps.24348. Epub 2015 Jan 12. J Pharm Sci. 2015. PMID: 25583633

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