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Targeted mutagenesis in a human-parasitic nematode.
Gang SS, Castelletto ML, Bryant AS, Yang E, Mancuso N, Lopez JB, Pellegrini M, Hallem EA. Gang SS, et al. Among authors: mancuso n. PLoS Pathog. 2017 Oct 10;13(10):e1006675. doi: 10.1371/journal.ppat.1006675. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 29016680 Free PMC article.
Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy.
Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry C, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rainbow K, Withers DJ, Cortessis V, Mullin PM, MacGibbon KW, Jin E, Kam A, Campbell A, Polasek O, Tzoneva G, Gribble FM, Yeo G, Lam B, Saudek V, Hughes IA, Ong KK, Perry J, Sutton Cole A, Baumgarten M, Welsh P, Sattar N, Smith G, Charnock Jones DS, Coll AP, Meek CL, Mettananda S, Hayward C, Mancuso N, O'Rahilly S. Fejzo M, et al. Among authors: mancuso n. bioRxiv [Preprint]. 2023 Jun 4:2023.06.02.542661. doi: 10.1101/2023.06.02.542661. bioRxiv. 2023. PMID: 37398065 Free PMC article. Preprint.
GDF15 linked to maternal risk of nausea and vomiting during pregnancy.
Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry CJ, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rimmington D, Rainbow K, Withers DJ, Cortessis V, Mullin PM, MacGibbon KW, Jin E, Kam A, Campbell A, Polasek O, Tzoneva G, Gribble FM, Yeo GSH, Lam BYH, Saudek V, Hughes IA, Ong KK, Perry JRB, Sutton Cole A, Baumgarten M, Welsh P, Sattar N, Smith GCS, Charnock-Jones DS, Coll AP, Meek CL, Mettananda S, Hayward C, Mancuso N, O'Rahilly S. Fejzo M, et al. Among authors: mancuso n. Nature. 2024 Jan;625(7996):760-767. doi: 10.1038/s41586-023-06921-9. Epub 2023 Dec 13. Nature. 2024. PMID: 38092039 Free PMC article.
A scalable variational approach to characterize pleiotropic components across thousands of human diseases and complex traits using GWAS summary statistics.
Zhang Z, Jung J, Kim A, Suboc N, Gazal S, Mancuso N. Zhang Z, et al. Among authors: mancuso n. medRxiv [Preprint]. 2023 Mar 29:2023.03.27.23287801. doi: 10.1101/2023.03.27.23287801. medRxiv. 2023. Update in: Am J Hum Genet. 2023 Nov 2;110(11):1863-1874. doi: 10.1016/j.ajhg.2023.09.015 PMID: 37034739 Free PMC article. Updated. Preprint.
96 results