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Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion.
Purcell RH, Sefik E, Werner E, King AT, Mosley TJ, Merritt-Garza ME, Chopra P, McEachin ZT, Karne S, Raj N, Vaglio BJ, Sullivan D, Firestein BL, Tilahun K, Robinette MI, Warren ST, Wen Z, Faundez V, Sloan SA, Bassell GJ, Mulle JG. Purcell RH, et al. Among authors: faundez v. bioRxiv [Preprint]. 2023 May 26:2023.01.27.525748. doi: 10.1101/2023.01.27.525748. bioRxiv. 2023. Update in: Sci Adv. 2023 Aug 18;9(33):eadh0558. doi: 10.1126/sciadv.adh0558 PMID: 36747819 Free PMC article. Updated. Preprint.
Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart.
Ohanele C, Peoples JN, Karlstaedt A, Geiger JT, Gayle AD, Ghazal N, Sohani F, Brown ME, Davis ME, Porter GA, Faundez V, Kwong JQ. Ohanele C, et al. Among authors: faundez v. bioRxiv [Preprint]. 2024 May 13:2023.05.22.541833. doi: 10.1101/2023.05.22.541833. bioRxiv. 2024. Update in: Commun Biol. 2024 Oct 31;7(1):1422. doi: 10.1038/s42003-024-07110-8 PMID: 37292906 Free PMC article. Updated. Preprint.
Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration.
Lane AR, Scher NE, Bhattacharjee S, Zlatic SA, Roberts AM, Gokhale A, Singleton KS, Duong DM, McKenna M, Liu WL, Baiju A, Moctezuma FGR, Tran T, Patel AA, Clayton LB, Petris MJ, Wood LB, Patgiri A, Vrailas-Mortimer AD, Cox DN, Roberts BR, Werner E, Faundez V. Lane AR, et al. Among authors: faundez v. bioRxiv [Preprint]. 2024 Nov 18:2024.09.09.612106. doi: 10.1101/2024.09.09.612106. bioRxiv. 2024. PMID: 39314281 Free PMC article. Preprint.
Schizophrenia: the "BLOC" may be in the endosomes.
Ryder PV, Faundez V. Ryder PV, et al. Among authors: faundez v. Sci Signal. 2009 Oct 20;2(93):pe66. doi: 10.1126/scisignal.293pe66. Sci Signal. 2009. PMID: 19843956 Free PMC article.
129 results