van Aalten DM - Search Results

1

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations.

Kumar A, Tamjar J, Waddell AD, Woodroof HI, Raimi OG, Shaw AM, Peggie M, Muqit MM, van Aalten DM. Kumar A, et al. Among authors: van aalten dm. Elife. 2017 Oct 5;6:e29985. doi: 10.7554/eLife.29985. Elife. 2017. PMID: 28980524 Free PMC article.

2

TAK1-binding protein 1 is a pseudophosphatase.

Conner SH, Kular G, Peggie M, Shepherd S, Schüttelkopf AW, Cohen P, Van Aalten DM. Conner SH, et al. Among authors: van aalten dm. Biochem J. 2006 Nov 1;399(3):427-34. doi: 10.1042/BJ20061077. Biochem J. 2006. PMID: 16879102 Free PMC article.

3

Glucose-6-phosphate as a probe for the glucosamine-6-phosphate N-acetyltransferase Michaelis complex.

Hurtado-Guerrero R, Raimi O, Shepherd S, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. FEBS Lett. 2007 Dec 11;581(29):5597-600. doi: 10.1016/j.febslet.2007.10.065. Epub 2007 Nov 20. FEBS Lett. 2007. PMID: 18005663 Free article.

4

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.

Hurtado-Guerrero R, Raimi OG, Min J, Zeng H, Vallius L, Shepherd S, Ibrahim AF, Wu H, Plotnikov AN, van Aalten DM. Hurtado-Guerrero R, et al. Among authors: van aalten dm. Biochem J. 2008 Oct 15;415(2):217-23. doi: 10.1042/BJ20081000. Biochem J. 2008. PMID: 18601654

5

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

Frearson JA, Brand S, McElroy SP, Cleghorn LA, Smid O, Stojanovski L, Price HP, Guther ML, Torrie LS, Robinson DA, Hallyburton I, Mpamhanga CP, Brannigan JA, Wilkinson AJ, Hodgkinson M, Hui R, Qiu W, Raimi OG, van Aalten DM, Brenk R, Gilbert IH, Read KD, Fairlamb AH, Ferguson MA, Smith DF, Wyatt PG. Frearson JA, et al. Among authors: van aalten dm. Nature. 2010 Apr 1;464(7289):728-32. doi: 10.1038/nature08893. Nature. 2010. PMID: 20360736 Free PMC article.

6

Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

Woodroof HI, Pogson JH, Begley M, Cantley LC, Deak M, Campbell DG, van Aalten DM, Whitworth AJ, Alessi DR, Muqit MM. Woodroof HI, et al. Among authors: van aalten dm. Open Biol. 2011 Nov;1(3):110012. doi: 10.1098/rsob.110012. Open Biol. 2011. PMID: 22645651 Free PMC article.

7

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target.

Fang W, Du T, Raimi OG, Hurtado-Guerrero R, Urbaniak MD, Ibrahim AF, Ferguson MA, Jin C, van Aalten DM. Fang W, et al. Among authors: van aalten dm. Mol Microbiol. 2013 Aug;89(3):479-93. doi: 10.1111/mmi.12290. Epub 2013 Jul 5. Mol Microbiol. 2013. PMID: 23750903 Free PMC article.

8

A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei.

Urbaniak MD, Collie IT, Fang W, Aristotelous T, Eskilsson S, Raimi OG, Harrison J, Navratilova IH, Frearson JA, van Aalten DM, Ferguson MA. Urbaniak MD, et al. Among authors: van aalten dm. ACS Chem Biol. 2013 Sep 20;8(9):1981-7. doi: 10.1021/cb400411x. Epub 2013 Jul 18. ACS Chem Biol. 2013. PMID: 23834437 Free PMC article.

9

Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target.

Fang W, Du T, Raimi OG, Hurtado-Guerrero R, Mariño K, Ibrahim AF, Albarbarawi O, Ferguson MA, Jin C, Van Aalten DM. Fang W, et al. Among authors: van aalten dm. Biosci Rep. 2013 Sep 4;33(5):e00063. doi: 10.1042/BSR20130053. Biosci Rep. 2013. PMID: 23844980 Free PMC article.

10

Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1.

Zhang N, Gordon SL, Fritsch MJ, Esoof N, Campbell DG, Gourlay R, Velupillai S, Macartney T, Peggie M, van Aalten DM, Cousin MA, Alessi DR. Zhang N, et al. Among authors: van aalten dm. J Neurosci. 2015 Feb 11;35(6):2492-507. doi: 10.1523/JNEUROSCI.4248-14.2015. J Neurosci. 2015. PMID: 25673844 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

210 results

Search Page

Filters