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The pan-BCL-2-blocker obatoclax (GX15-070) and the PI3-kinase/mTOR-inhibitor BEZ235 produce cooperative growth-inhibitory effects in ALL cells.
Stefanzl G, Berger D, Cerny-Reiterer S, Blatt K, Eisenwort G, Sperr WR, Hoermann G, Lind K, Hauswirth AW, Bettelheim P, Sill H, Melo JV, Jäger U, Valent P. Stefanzl G, et al. Among authors: lind k. Oncotarget. 2017 Jun 28;8(40):67709-67722. doi: 10.18632/oncotarget.18810. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978065 Free PMC article.
Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia.
Zebisch A, Wölfler A, Fried I, Wolf O, Lind K, Bodner C, Haller M, Drasche A, Pirkebner D, Matallanas D, Rath O, Blyth K, Delwel R, Taskesen E, Quehenberger F, Kolch W, Troppmair J, Sill H. Zebisch A, et al. Among authors: lind k. Leukemia. 2012 Aug;26(8):1842-9. doi: 10.1038/leu.2012.61. Epub 2012 Mar 5. Leukemia. 2012. PMID: 22388727
Acute myeloid leukemia with TP53 germ line mutations.
Zebisch A, Lal R, Müller M, Lind K, Kashofer K, Girschikofsky M, Fuchs D, Wölfler A, Geigl JB, Sill H. Zebisch A, et al. Among authors: lind k. Blood. 2016 Nov 3;128(18):2270-2272. doi: 10.1182/blood-2016-08-732610. Epub 2016 Sep 12. Blood. 2016. PMID: 27621308 Free PMC article. No abstract available.
STAT3β is a tumor suppressor in acute myeloid leukemia.
Aigner P, Mizutani T, Horvath J, Eder T, Heber S, Lind K, Just V, Moll HP, Yeroslaviz A, Fischer MJM, Kenner L, Győrffy B, Sill H, Grebien F, Moriggl R, Casanova E, Stoiber D. Aigner P, et al. Among authors: lind k. Blood Adv. 2019 Jul 9;3(13):1989-2002. doi: 10.1182/bloodadvances.2018026385. Blood Adv. 2019. PMID: 31270081 Free PMC article.
Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter.
van der Kouwe E, Heller G, Czibere A, Pulikkan JA, Agreiter C, Castilla LH, Delwel R, Di Ruscio A, Ebralidze AK, Forte M, Grebien F, Heyes E, Kazianka L, Klinger J, Kornauth C, Le T, Lind K, Barbosa IAM, Pemovska T, Pichler A, Schmolke AS, Schweicker CM, Sill H, Sperr WR, Spittler A, Surapally S, Trinh BQ, Valent P, Vanura K, Welner RS, Zuber J, Tenen DG, Staber PB. van der Kouwe E, et al. Among authors: lind k. Blood. 2021 Oct 14;138(15):1345-1358. doi: 10.1182/blood.2020008971. Blood. 2021. PMID: 34010414 Free PMC article.
366 results