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Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures.
Finnberg NK, Gokare P, Lev A, Grivennikov SI, MacFarlane AW 4th, Campbell KS, Winters RM, Kaputa K, Farma JM, Abbas AE, Grasso L, Nicolaides NC, El-Deiry WS. Finnberg NK, et al. Among authors: nicolaides nc. Oncotarget. 2017 Aug 5;8(40):66747-66757. doi: 10.18632/oncotarget.19965. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28977993 Free PMC article.
Rapid generation of plant traits via regulation of DNA mismatch repair.
Chao Q, Sullivan CD, Getz JM, Gleason KB, Sass PM, Nicolaides NC, Grasso L. Chao Q, et al. Among authors: nicolaides nc. Plant Biotechnol J. 2005 Jul;3(4):399-407. doi: 10.1111/j.1467-7652.2005.00133.x. Plant Biotechnol J. 2005. PMID: 17173628 Free article.
Advances in targeted therapeutic agents.
Nicolaides NC, Sass PM, Grasso L. Nicolaides NC, et al. Expert Opin Drug Discov. 2010 Nov;5(11):1123-40. doi: 10.1517/17460441.2010.521496. Epub 2010 Oct 1. Expert Opin Drug Discov. 2010. PMID: 22827748 Review.
Developing novel biopharmaceutical products through morphogenics.
Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L. Nicolaides NC, et al. Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619. Expert Opin Drug Discov. 2007. PMID: 23488905
The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
Lin J, Spidel JL, Maddage CJ, Rybinski KA, Kennedy RP, Krauthauser CL, Park YC, Albone EF, Jacob S, Goserud MT, Martinez BP, Chao Q, Zhou Y, Nicolaides NC, Kline JB, Grasso L. Lin J, et al. Among authors: nicolaides nc. Cancer Biol Ther. 2013 Nov;14(11):1032-8. doi: 10.4161/cbt.26106. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025360 Free PMC article.
Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin.
Chacko AM, Li C, Nayak M, Mikitsh JL, Hu J, Hou C, Grasso L, Nicolaides NC, Muzykantov VR, Divgi CR, Coukos G. Chacko AM, et al. Among authors: nicolaides nc. J Nucl Med. 2014 Mar;55(3):500-507. doi: 10.2967/jnumed.113.121905. Epub 2014 Feb 13. J Nucl Med. 2014. PMID: 24525208 Free PMC article.
136 results