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L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2.
Kou L, Hou Y, Yao Q, Guo W, Wang G, Wang M, Fu Q, He Z, Ganapathy V, Sun J. Kou L, et al. Among authors: sun j. Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1605-1616. doi: 10.1080/21691401.2017.1384385. Epub 2017 Oct 3. Artif Cells Nanomed Biotechnol. 2018. PMID: 28974108 Free article.
Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs.
Kou L, Yao Q, Sun M, Wu C, Wang J, Luo Q, Wang G, Du Y, Fu Q, Wang J, He Z, Ganapathy V, Sun J. Kou L, et al. Among authors: sun m, sun j. Adv Healthc Mater. 2017 Sep;6(17). doi: 10.1002/adhm.201700165. Epub 2017 Jun 29. Adv Healthc Mater. 2017. PMID: 28661032
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