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Page 1
Evaluation of aminohydantoins as a novel class of antimalarial agents.
Meyers MJ, Tortorella MD, Xu J, Qin L, He Z, Lang X, Zeng W, Xu W, Qin L, Prinsen MJ, Sverdrup FM, Eickhoff CS, Griggs DW, Oliva J, Ruminski PG, Jacobsen EJ, Campbell MA, Wood DC, Goldberg DE, Liu X, Lu Y, Lu X, Tu Z, Lu X, Ding K, Chen X. Meyers MJ, et al. ACS Med Chem Lett. 2013 Dec 6;5(1):89-93. doi: 10.1021/ml400412x. eCollection 2014 Jan 9. ACS Med Chem Lett. 2013. PMID: 24900778 Free PMC article.
Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents.
Meyers MJ, Anderson EJ, McNitt SA, Krenning TM, Singh M, Xu J, Zeng W, Qin L, Xu W, Zhao S, Qin L, Eickhoff CS, Oliva J, Campbell MA, Arnett SD, Prinsen MJ, Griggs DW, Ruminski PG, Goldberg DE, Ding K, Liu X, Tu Z, Tortorella MD, Sverdrup FM, Chen X. Meyers MJ, et al. Bioorg Med Chem. 2015 Aug 15;23(16):5144-50. doi: 10.1016/j.bmc.2015.02.050. Epub 2015 Mar 4. Bioorg Med Chem. 2015. PMID: 25797165 Free PMC article.
Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea.
Griggs DW, Prinsen MJ, Oliva J, Campbell MA, Arnett SD, Tajfirouz D, Ruminski PG, Yu Y, Bond BR, Ji Y, Neckermann G, Choy RK, de Hostos E, Meyers MJ. Griggs DW, et al. Among authors: meyers mj. J Pharmacol Exp Ther. 2016 May;357(2):423-31. doi: 10.1124/jpet.115.231167. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907621 Free PMC article.
A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box.
Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD. Jumani RS, et al. Among authors: meyers mj. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01505-17. doi: 10.1128/AAC.01505-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29339392 Free PMC article.
Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin.
Oboh E, Schubert TJ, Teixeira JE, Stebbins EE, Miller P, Philo E, Thakellapalli H, Campbell SD, Griggs DW, Huston CD, Meyers MJ. Oboh E, et al. Among authors: meyers mj. J Med Chem. 2021 Aug 12;64(15):11729-11745. doi: 10.1021/acs.jmedchem.1c01136. Epub 2021 Aug 3. J Med Chem. 2021. PMID: 34342443 Free PMC article.
Comparative chemical genomics in Babesia species identifies the alkaline phosphatase PhoD as a determinant of antiparasitic resistance.
Keroack CD, Elsworth B, Tennessen JA, Paul AS, Hua R, Ramirez-Ramirez L, Ye S, Moreira CK, Meyers MJ, Zarringhalam K, Duraisingh MT. Keroack CD, et al. Among authors: meyers mj. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2312987121. doi: 10.1073/pnas.2312987121. Epub 2024 Feb 20. Proc Natl Acad Sci U S A. 2024. PMID: 38377214 Free PMC article.
Structure-Activity Relationship Studies of the Aryl Acetamide Triazolopyridazines against Cryptosporidium Reveals Remarkable Role of Fluorine.
Schubert TJ, Oboh E, Peek H, Philo E, Teixeira JE, Stebbins EE, Miller P, Oliva J, Sverdrup FM, Griggs DW, Huston CD, Meyers MJ. Schubert TJ, et al. Among authors: meyers mj. J Med Chem. 2023 Jun 22;66(12):7834-7848. doi: 10.1021/acs.jmedchem.3c00110. Epub 2023 Jun 2. J Med Chem. 2023. PMID: 37267631 Free PMC article.
81 results