Zhu X - Search Results

1

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.

Zhu X, Hu T, Ho MH, Wang Y, Yu M, Patel N, Pi W, Choi JH, Xu H, Ganapathy V, Kutlar F, Kutlar A, Tuan D. Zhu X, et al. Haematologica. 2017 Dec;102(12):1995-2004. doi: 10.3324/haematol.2017.175646. Epub 2017 Sep 29. Haematologica. 2017. PMID: 28971909 Free PMC article.

2

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2.

Yu X, Zhu X, Pi W, Ling J, Ko L, Takeda Y, Tuan D. Yu X, et al. Among authors: zhu x. J Biol Chem. 2005 Oct 21;280(42):35184-94. doi: 10.1074/jbc.M508138200. Epub 2005 Aug 16. J Biol Chem. 2005. PMID: 16105833 Free article.

3

A facilitated tracking and transcription mechanism of long-range enhancer function.

Zhu X, Ling J, Zhang L, Pi W, Wu M, Tuan D. Zhu X, et al. Nucleic Acids Res. 2007;35(16):5532-44. doi: 10.1093/nar/gkm595. Epub 2007 Aug 17. Nucleic Acids Res. 2007. PMID: 17704132 Free PMC article.

4

Long-range function of an intergenic retrotransposon.

Pi W, Zhu X, Wu M, Wang Y, Fulzele S, Eroglu A, Ling J, Tuan D. Pi W, et al. Among authors: zhu x. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12992-7. doi: 10.1073/pnas.1004139107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615953 Free PMC article.

5

NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene.

Zhu X, Wang Y, Pi W, Liu H, Wickrema A, Tuan D. Zhu X, et al. PLoS One. 2012;7(10):e47175. doi: 10.1371/journal.pone.0047175. Epub 2012 Oct 10. PLoS One. 2012. PMID: 23071749 Free PMC article.

6

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function.

Hu T, Pi W, Zhu X, Yu M, Ha H, Shi H, Choi JH, Tuan D. Hu T, et al. Among authors: zhu x. Nucleic Acids Res. 2017 May 5;45(8):4479-4492. doi: 10.1093/nar/gkx055. Nucleic Acids Res. 2017. PMID: 28132025 Free PMC article.

7

Hypermethylated LTR retrotransposon exhibits enhancer activity.

Hu T, Zhu X, Pi W, Yu M, Shi H, Tuan D. Hu T, et al. Among authors: zhu x. Epigenetics. 2017 Mar 4;12(3):226-237. doi: 10.1080/15592294.2017.1289300. Epub 2017 Feb 6. Epigenetics. 2017. PMID: 28165867 Free PMC article.

8

NRF2 mediates γ-globin gene regulation and fetal hemoglobin induction in human erythroid progenitors.

Zhu X, Li B, Pace BS. Zhu X, et al. Haematologica. 2017 Aug;102(8):e285-e288. doi: 10.3324/haematol.2016.160788. Epub 2017 May 4. Haematologica. 2017. PMID: 28473619 Free PMC article. No abstract available.

9

Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model.

Zhu X, Xi C, Thomas B, Pace BS. Zhu X, et al. Blood. 2018 Feb 1;131(5):558-562. doi: 10.1182/blood-2017-10-810531. Epub 2017 Dec 18. Blood. 2018. PMID: 29255069 Free PMC article.

10

Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain.

Li B, Zhu X, Hossain MA, Guy CR, Xu H, Bungert J, Pace BS. Li B, et al. Among authors: zhu x. Haematologica. 2018 Sep;103(9):e384-e387. doi: 10.3324/haematol.2017.185967. Epub 2018 Apr 5. Haematologica. 2018. PMID: 29622657 Free PMC article. No abstract available.

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