Gestwicki JE - Search Results

1

Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades.

Srinivasan SR, Cesa LC, Li X, Julien O, Zhuang M, Shao H, Chung J, Maillard I, Wells JA, Duckett CS, Gestwicki JE. Srinivasan SR, et al. Among authors: gestwicki je. Mol Cancer Res. 2018 Jan;16(1):58-68. doi: 10.1158/1541-7786.MCR-17-0408. Epub 2017 Sep 28. Mol Cancer Res. 2018. PMID: 28970360 Free PMC article.

2

Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase.

Wisén S, Androsavich J, Evans CG, Chang L, Gestwicki JE. Wisén S, et al. Among authors: gestwicki je. Bioorg Med Chem Lett. 2008 Jan 1;18(1):60-5. doi: 10.1016/j.bmcl.2007.11.027. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18060774

3

Pharmacological targeting of the Hsp70 chaperone.

Patury S, Miyata Y, Gestwicki JE. Patury S, et al. Among authors: gestwicki je. Curr Top Med Chem. 2009;9(15):1337-51. doi: 10.2174/156802609789895674. Curr Top Med Chem. 2009. PMID: 19860737 Free PMC article. Review.

4

Heat shock protein 70 (hsp70) as an emerging drug target.

Evans CG, Chang L, Gestwicki JE. Evans CG, et al. Among authors: gestwicki je. J Med Chem. 2010 Jun 24;53(12):4585-602. doi: 10.1021/jm100054f. J Med Chem. 2010. PMID: 20334364 Free PMC article. Review. No abstract available.

5

Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.

Wang AM, Morishima Y, Clapp KM, Peng HM, Pratt WB, Gestwicki JE, Osawa Y, Lieberman AP. Wang AM, et al. Among authors: gestwicki je. J Biol Chem. 2010 May 21;285(21):15714-23. doi: 10.1074/jbc.M109.098806. Epub 2010 Mar 26. J Biol Chem. 2010. PMID: 20348093 Free PMC article.

6

Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

Wisén S, Bertelsen EB, Thompson AD, Patury S, Ung P, Chang L, Evans CG, Walter GM, Wipf P, Carlson HA, Brodsky JL, Zuiderweg ER, Gestwicki JE. Wisén S, et al. Among authors: gestwicki je. ACS Chem Biol. 2010 Jun 18;5(6):611-22. doi: 10.1021/cb1000422. ACS Chem Biol. 2010. PMID: 20481474 Free PMC article.

7

High-throughput screen for Escherichia coli heat shock protein 70 (Hsp70/DnaK): ATPase assay in low volume by exploiting energy transfer.

Miyata Y, Chang L, Bainor A, McQuade TJ, Walczak CP, Zhang Y, Larsen MJ, Kirchhoff P, Gestwicki JE. Miyata Y, et al. Among authors: gestwicki je. J Biomol Screen. 2010 Dec;15(10):1211-9. doi: 10.1177/1087057110380571. Epub 2010 Oct 6. J Biomol Screen. 2010. PMID: 20926844 Free PMC article.

8

Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones.

Rousaki A, Miyata Y, Jinwal UK, Dickey CA, Gestwicki JE, Zuiderweg ER. Rousaki A, et al. Among authors: gestwicki je. J Mol Biol. 2011 Aug 19;411(3):614-32. doi: 10.1016/j.jmb.2011.06.003. Epub 2011 Jun 25. J Mol Biol. 2011. PMID: 21708173 Free PMC article.

9

Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.

Walter GM, Smith MC, Wisén S, Basrur V, Elenitoba-Johnson KS, Duennwald ML, Kumar A, Gestwicki JE. Walter GM, et al. Among authors: gestwicki je. J Biol Chem. 2011 Nov 25;286(47):40486-93. doi: 10.1074/jbc.M111.284448. Epub 2011 Oct 3. J Biol Chem. 2011. PMID: 21969373 Free PMC article.

10

Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK).

Thompson AD, Bernard SM, Skiniotis G, Gestwicki JE. Thompson AD, et al. Among authors: gestwicki je. Cell Stress Chaperones. 2012 May;17(3):313-27. doi: 10.1007/s12192-011-0307-1. Epub 2011 Nov 11. Cell Stress Chaperones. 2012. PMID: 22076723 Free PMC article.

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