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Page 1
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.
Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, Sogne E, Falqui A, Petricca L, Verani M, Martufi P, Caricasole A, Bresciani A, Cecchetti O, Rivetti di Val Cervo P, Sancini G, Riess O, Nguyen H, Seipold L, Saftig P, Biella G, Cattaneo E, Zuccato C. Vezzoli E, et al. Among authors: falqui a. J Clin Invest. 2019 May 6;129(6):2390-2403. doi: 10.1172/JCI120616. eCollection 2019 May 6. J Clin Invest. 2019. PMID: 31063986 Free PMC article.
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
Birolini G, Valenza M, Di Paolo E, Vezzoli E, Talpo F, Maniezzi C, Caccia C, Leoni V, Taroni F, Bocchi VD, Conforti P, Sogne E, Petricca L, Cariulo C, Verani M, Caricasole A, Falqui A, Biella G, Cattaneo E. Birolini G, et al. Among authors: falqui a. EMBO Mol Med. 2020 Oct 7;12(10):e12519. doi: 10.15252/emmm.202012519. Epub 2020 Sep 22. EMBO Mol Med. 2020. PMID: 32959531 Free PMC article.
Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.
Galimberti M, Nucera MR, Bocchi VD, Conforti P, Vezzoli E, Cereda M, Maffezzini C, Iennaco R, Scolz A, Falqui A, Cordiglieri C, Cremona M, Espuny-Camacho I, Faedo A, Felsenfeld DP, Vogt TF, Ranzani V, Zuccato C, Besusso D, Cattaneo E. Galimberti M, et al. Among authors: falqui a. Nat Commun. 2024 Aug 2;15(1):6534. doi: 10.1038/s41467-024-50877-x. Nat Commun. 2024. PMID: 39095390 Free PMC article.
Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations.
D'Ambrosio A, Bressan D, Ferracci E, Carbone F, Mulè P, Rossi F, Barbieri C, Sorrenti E, Fiaccadori G, Detone T, Vezzoli E, Bianchi S, Sartori C, Corso S, Fukuda A, Bertalot G, Falqui A, Barbareschi M, Romanel A, Pasini D, Chiacchiera F. D'Ambrosio A, et al. Among authors: falqui a. Sci Adv. 2024 Mar 15;10(11):eadh4435. doi: 10.1126/sciadv.adh4435. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489371 Free PMC article.
122 results