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Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies.
Ang Z, Paruzzo L, Hayer KE, Schmidt C, Torres Diz M, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, King Sainos P, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Lieberman PM, Ruella M, Schuster SJ, Thomas-Tikhonenko A. Ang Z, et al. Among authors: barash y. bioRxiv [Preprint]. 2023 Aug 16:2023.02.19.529123. doi: 10.1101/2023.02.19.529123. bioRxiv. 2023. Update in: Blood. 2023 Nov 16;142(20):1724-1739. doi: 10.1182/blood.2023020400 PMID: 37645778 Free PMC article. Updated. Preprint.
ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.
Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ. Rohacek AM, et al. Among authors: barash y. Dev Cell. 2017 Nov 6;43(3):318-331.e5. doi: 10.1016/j.devcel.2017.09.026. Epub 2017 Oct 26. Dev Cell. 2017. PMID: 29107558 Free PMC article.
RNA splicing analysis using heterogeneous and large RNA-seq datasets.
Vaquero-Garcia J, Aicher JK, Jewell S, Gazzara MR, Radens CM, Jha A, Norton SS, Lahens NF, Grant GR, Barash Y. Vaquero-Garcia J, et al. Among authors: barash y. Nat Commun. 2023 Mar 3;14(1):1230. doi: 10.1038/s41467-023-36585-y. Nat Commun. 2023. PMID: 36869033 Free PMC article.
167 results