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Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.
Deckx S, Heggermont W, Carai P, Rienks M, Dresselaers T, Himmelreich U, van Leeuwen R, Lommen W, van der Velden J, Gonzalez A, Diez J, Papageorgiou AP, Heymans S. Deckx S, et al. Among authors: van leeuwen r, van der velden j. Matrix Biol. 2018 Mar;66:110-124. doi: 10.1016/j.matbio.2017.09.002. Epub 2017 Sep 25. Matrix Biol. 2018. PMID: 28958774
Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy.
Schroen B, Heymans S, Sharma U, Blankesteijn WM, Pokharel S, Cleutjens JP, Porter JG, Evelo CT, Duisters R, van Leeuwen RE, Janssen BJ, Debets JJ, Smits JF, Daemen MJ, Crijns HJ, Bornstein P, Pinto YM. Schroen B, et al. Among authors: van leeuwen re. Circ Res. 2004 Sep 3;95(5):515-22. doi: 10.1161/01.RES.0000141019.20332.3e. Epub 2004 Jul 29. Circ Res. 2004. PMID: 15284191
Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.
Schroen B, Leenders JJ, van Erk A, Bertrand AT, van Loon M, van Leeuwen RE, Kubben N, Duisters RF, Schellings MW, Janssen BJ, Debets JJ, Schwake M, Høydal MA, Heymans S, Saftig P, Pinto YM. Schroen B, et al. J Exp Med. 2007 May 14;204(5):1227-35. doi: 10.1084/jem.20070145. Epub 2007 May 7. J Exp Med. 2007. PMID: 17485520 Free PMC article.
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling.
Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, Herias V, van Leeuwen RE, Schellings MW, Barenbrug P, Maessen JG, Heymans S, Pinto YM, Creemers EE. Duisters RF, et al. Circ Res. 2009 Jan 30;104(2):170-8, 6p following 178. doi: 10.1161/CIRCRESAHA.108.182535. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096030
Syndecan-1 amplifies angiotensin II-induced cardiac fibrosis.
Schellings MW, Vanhoutte D, van Almen GC, Swinnen M, Leenders JJ, Kubben N, van Leeuwen RE, Hofstra L, Heymans S, Pinto YM. Schellings MW, et al. Hypertension. 2010 Feb;55(2):249-56. doi: 10.1161/HYPERTENSIONAHA.109.137885. Epub 2010 Jan 4. Hypertension. 2010. PMID: 20048198 Free article.
Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity.
Leenders JJ, Wijnen WJ, Hiller M, van der Made I, Lentink V, van Leeuwen REW, Herias V, Pokharel S, Heymans S, de Windt LJ, Høydal MA, Pinto YM, Creemers EE. Leenders JJ, et al. J Biol Chem. 2010 Aug 27;285(35):27449-27456. doi: 10.1074/jbc.M110.107292. Epub 2010 Jun 21. J Biol Chem. 2010. PMID: 20566642 Free PMC article.
MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis.
Corsten MF, Papageorgiou A, Verhesen W, Carai P, Lindow M, Obad S, Summer G, Coort SL, Hazebroek M, van Leeuwen R, Gijbels MJ, Wijnands E, Biessen EA, De Winther MP, Stassen FR, Carmeliet P, Kauppinen S, Schroen B, Heymans S. Corsten MF, et al. Among authors: van leeuwen r. Circ Res. 2012 Aug 3;111(4):415-25. doi: 10.1161/CIRCRESAHA.112.267443. Epub 2012 Jun 19. Circ Res. 2012. PMID: 22715471
384 results