Okamoto K - Search Results

1

A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice.

Ito R, Nagai D, Igo N, Okuda Y, Sekine K, Ichimura E, Katano I, Mizushima T, Goto M, Ohnishi Y, Ito M, Okamoto K. Ito R, et al. Among authors: okamoto k. Toxicol Lett. 2017 Nov 5;281:152-157. doi: 10.1016/j.toxlet.2017.09.013. Epub 2017 Sep 22. Toxicol Lett. 2017. PMID: 28947270

2

Preclinical anticancer effects and toxicologic assessment of hepatic artery infusion of fine-powder cisplatin with lipiodol in vivo.

Yamaguchi T, Nakajima N, Nakamura I, Mashiba H, Kawashiro T, Ebara K, Ichimura E, Nishimura C, Okamoto K, Ichikawa Y, Ichida T. Yamaguchi T, et al. Among authors: okamoto k. Drug Discov Ther. 2013 Oct;7(5):201-8. Drug Discov Ther. 2013. PMID: 24270385 Free article.

3

Antimyeloma activity of NK012, a micelle-forming macromolecular prodrug of SN-38, in an orthotopic model.

Miyazaki O, Sekine K, Nakajima N, Ichimura E, Ebara K, Nagai D, Onda T, Miyakawa Y, Okamoto K, Morino T. Miyazaki O, et al. Among authors: okamoto k. Int J Cancer. 2014 Jan 1;134(1):218-23. doi: 10.1002/ijc.28333. Epub 2013 Jul 16. Int J Cancer. 2014. PMID: 23775066

4

Comparative study of peripheral neurotoxicity after injection of two different paclitaxel formulations in rats.

Nakamura I, Ichimura E, Kobayashi H, Mashiba H, Nagai D, Ebara K, Hayashi H, Okamoto K, Wake N, Nishikawa K. Nakamura I, et al. Among authors: okamoto k. Arzneimittelforschung. 2010;60(4):205-9. doi: 10.1055/s-0031-1296274. Arzneimittelforschung. 2010. PMID: 20486471

5

NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors.

Onda T, Toyoda E, Miyazaki O, Seno C, Kagaya S, Okamoto K, Nishikawa K. Onda T, et al. Among authors: okamoto k. Cancer Lett. 2008 Jan 18;259(1):99-110. doi: 10.1016/j.canlet.2007.10.004. Epub 2007 Nov 12. Cancer Lett. 2008. PMID: 17998154

6

Development of the polymer micelle carrier system for doxorubicin.

Nakanishi T, Fukushima S, Okamoto K, Suzuki M, Matsumura Y, Yokoyama M, Okano T, Sakurai Y, Kataoka K. Nakanishi T, et al. Among authors: okamoto k. J Control Release. 2001 Jul 6;74(1-3):295-302. doi: 10.1016/s0168-3659(01)00341-8. J Control Release. 2001. PMID: 11489509

7

Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor.

Yokoyama M, Fukushima S, Uehara R, Okamoto K, Kataoka K, Sakurai Y, Okano T. Yokoyama M, et al. Among authors: okamoto k. J Control Release. 1998 Jan 2;50(1-3):79-92. doi: 10.1016/s0168-3659(97)00115-6. J Control Release. 1998. PMID: 9685875

8

Urodele amphibian newt bridges the missing link in evo-devo of the pancreas.

Morozumi R, Okamoto K, Enomoto E, Tsukamoto Y, Kyakuno M, Suzuki N, Tazawa I, Furuno N, Ogino H, Kamei Y, Matsunami M, Shigenobu S, Suzuki K, Uemasu H, Namba N, Hayashi T. Morozumi R, et al. Among authors: okamoto k. Dev Dyn. 2025 Jan 8. doi: 10.1002/dvdy.763. Online ahead of print. Dev Dyn. 2025. PMID: 39777819

9

Effect of Cdk1 gene disruption on cell cycle progression in newt cells.

Nakao Y, Okamoto K, Tazawa I, Nishijima T, Furuno N, Sakuma T, Yamamoto T, Takeuchi T, Hayashi T. Nakao Y, et al. Among authors: okamoto k. Dev Growth Differ. 2025 Jan 8. doi: 10.1111/dgd.12958. Online ahead of print. Dev Growth Differ. 2025. PMID: 39776058

10

Defluorinative functionalization approach led by difluoromethyl anion chemistry.

Muta K, Okamoto K, Nakayama H, Wada S, Nagaki A. Muta K, et al. Among authors: okamoto k. Nat Commun. 2025 Jan 7;16(1):416. doi: 10.1038/s41467-024-52842-0. Nat Commun. 2025. PMID: 39774136 Free PMC article.

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