Klingstedt T - Search Results

1

Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-β deposits.

Klingstedt T, Shirani H, Parvin F, Nyström S, Hammarström P, Graff C, Ingelsson M, Vidal R, Ghetti B, Sehlin D, Syvänen S, Nilsson KPR. Klingstedt T, et al. J Biol Chem. 2024 Nov 29;301(1):108032. doi: 10.1016/j.jbc.2024.108032. Online ahead of print. J Biol Chem. 2024. PMID: 39615691 Free PMC article.

2

In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging.

Swaminathan P, Klingstedt T, Theologidis V, Gram H, Larsson J, Hagen L, Liabakk NB, Gederaas OA, Hammarström P, Nilsson KPR, Van Den Berge N, Lindgren M. Swaminathan P, et al. Among authors: klingstedt t. Int J Mol Sci. 2024 Nov 20;25(22):12458. doi: 10.3390/ijms252212458. Int J Mol Sci. 2024. PMID: 39596523 Free PMC article.

3

Distinct Chemical Determinants are Essential for Achieving Ligands for Superior Optical Detection of Specific Amyloid-β Deposits in Alzheimer's Disease.

Wu X, Shirani H, Vidal R, Ghetti B, Ingelsson M, Klingstedt T, Nilsson KPR. Wu X, et al. Among authors: klingstedt t. ChemistryOpen. 2024 Dec;13(12):e202400186. doi: 10.1002/open.202400186. Epub 2024 Nov 7. ChemistryOpen. 2024. PMID: 39508558 Free PMC article.

4

In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references.

Rautio T, Obrist R, Krebs L, Klingstedt T, Dahlén J, Wu X, Gréen H. Rautio T, et al. Among authors: klingstedt t. Drug Test Anal. 2024 Jul 23. doi: 10.1002/dta.3773. Online ahead of print. Drug Test Anal. 2024. PMID: 39039949

5

Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands Towards Aβ or Tau Pathology in Alzheime's Disease.

Björk L, Shirani H, Todarwal Y, Linares M, Vidal R, Ghetti B, Norman P, Klingstedt T, Nilsson KPR. Björk L, et al. Among authors: klingstedt t. European J Org Chem. 2023 Nov 2;26(41):e202300583. doi: 10.1002/ejoc.202300583. Epub 2023 Sep 11. European J Org Chem. 2023. PMID: 38585413 Free PMC article.

6

Thiophene-Based Ligands for Specific Assignment of Distinct Aβ Pathologies in Alzheimer's Disease.

Klingstedt T, Lantz L, Shirani H, Ge J, Hanrieder J, Vidal R, Ghetti B, Nilsson KPR. Klingstedt T, et al. ACS Chem Neurosci. 2024 Apr 3;15(7):1581-1595. doi: 10.1021/acschemneuro.4c00021. Epub 2024 Mar 24. ACS Chem Neurosci. 2024. PMID: 38523263 Free PMC article.

7

A Novel Drosophila Model of Alzheimer's Disease to Study Aβ Proteotoxicity in the Digestive Tract.

Elovsson G, Klingstedt T, Brown M, Nilsson KPR, Brorsson AC. Elovsson G, et al. Among authors: klingstedt t. Int J Mol Sci. 2024 Feb 9;25(4):2105. doi: 10.3390/ijms25042105. Int J Mol Sci. 2024. PMID: 38396782 Free PMC article.

8

Mutation ∆K281 in MAPT causes Pick's disease.

Schweighauser M, Garringer HJ, Klingstedt T, Nilsson KPR, Masuda-Suzukake M, Murrell JR, Risacher SL, Vidal R, Scheres SHW, Goedert M, Ghetti B, Newell KL. Schweighauser M, et al. Among authors: klingstedt t. Acta Neuropathol. 2023 Aug;146(2):211-226. doi: 10.1007/s00401-023-02598-6. Epub 2023 Jun 23. Acta Neuropathol. 2023. PMID: 37351604 Free PMC article.

9

Thiophene-Based Ligands: Design, Synthesis and Their Utilization for Optical Assignment of Polymorphic-Disease-Associated Protein Aggregates.

Björk L, Klingstedt T, Nilsson KPR. Björk L, et al. Among authors: klingstedt t. Chembiochem. 2023 Jun 1;24(11):e202300044. doi: 10.1002/cbic.202300044. Epub 2023 May 8. Chembiochem. 2023. PMID: 36891883 Free PMC article. Review.

10

Thiophene-Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease.

Lantz L, Shirani H, Ghetti B, Vidal R, Klingstedt T, Nilsson KPR. Lantz L, et al. Among authors: klingstedt t. Chemistry. 2023 Apr 13;29(21):e202203568. doi: 10.1002/chem.202203568. Epub 2023 Mar 8. Chemistry. 2023. PMID: 36645413 Free PMC article.

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