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High-throughput functional genomics using CRISPR-Cas9.
Shalem O, Sanjana NE, Zhang F. Shalem O, et al. Among authors: sanjana ne. Nat Rev Genet. 2015 May;16(5):299-311. doi: 10.1038/nrg3899. Epub 2015 Apr 9. Nat Rev Genet. 2015. PMID: 25854182 Free PMC article. Review.
CRISPR Screens to Discover Functional Noncoding Elements.
Wright JB, Sanjana NE. Wright JB, et al. Among authors: sanjana ne. Trends Genet. 2016 Sep;32(9):526-529. doi: 10.1016/j.tig.2016.06.004. Epub 2016 Jul 13. Trends Genet. 2016. PMID: 27423542 Free PMC article. Review.
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.
Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Joung J, et al. Among authors: sanjana ne. Nat Protoc. 2017 Apr;12(4):828-863. doi: 10.1038/nprot.2017.016. Epub 2017 Mar 23. Nat Protoc. 2017. PMID: 28333914 Free PMC article.
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Joung J, et al. Among authors: sanjana ne. Nature. 2017 Aug 17;548(7667):343-346. doi: 10.1038/nature23451. Epub 2017 Aug 11. Nature. 2017. PMID: 28792927 Free PMC article.
GUIDES: sgRNA design for loss-of-function screens.
Meier JA, Zhang F, Sanjana NE. Meier JA, et al. Among authors: sanjana ne. Nat Methods. 2017 Aug 31;14(9):831-832. doi: 10.1038/nmeth.4423. Nat Methods. 2017. PMID: 28858339 Free PMC article. No abstract available.
82 results