Identification of formaldehyde-induced modifications in proteins: reactions with insulin.
Metz B, Kersten GF, Baart GJ, de Jong A, Meiring H, ten Hove J, van Steenbergen MJ, Hennink WE, Crommelin DJ, Jiskoot W.
Metz B, et al.
Bioconjug Chem. 2006 May-Jun;17(3):815-22. doi: 10.1021/bc050340f.
Bioconjug Chem. 2006.
PMID: 16704222
Both the location and the chemical nature of the modifications could be assigned based on the mass increase of potential adducts as elucidated in our previous study (B. Metz et al. (2004) J. Biol. Chem. 279, 6235-6243). To confirm the assigned structures, LC-MS meas …
Both the location and the chemical nature of the modifications could be assigned based on the mass increase of potential adducts as elucidat …