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Page 1
How Ribosomes Translate Cancer.
Sulima SO, Hofman IJF, De Keersmaecker K, Dinman JD. Sulima SO, et al. Among authors: de keersmaecker k. Cancer Discov. 2017 Oct;7(10):1069-1087. doi: 10.1158/2159-8290.CD-17-0550. Epub 2017 Sep 18. Cancer Discov. 2017. PMID: 28923911 Free PMC article. Review.
Bypass of the pre-60S ribosomal quality control as a pathway to oncogenesis.
Sulima SO, Patchett S, Advani VM, De Keersmaecker K, Johnson AW, Dinman JD. Sulima SO, et al. Among authors: de keersmaecker k. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5640-5. doi: 10.1073/pnas.1400247111. Epub 2014 Mar 31. Proc Natl Acad Sci U S A. 2014. PMID: 24706786 Free PMC article.
RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response.
Hofman IJF, van Duin M, De Bruyne E, Fancello L, Mulligan G, Geerdens E, Garelli E, Mancini C, Lemmens H, Delforge M, Vandenberghe P, Wlodarska I, Aspesi A, Michaux L, Vanderkerken K, Sonneveld P, De Keersmaecker K. Hofman IJF, et al. Among authors: de bruyne e, de keersmaecker k. Leukemia. 2017 Aug;31(8):1706-1714. doi: 10.1038/leu.2016.370. Epub 2016 Dec 2. Leukemia. 2017. PMID: 27909306 Free PMC article.
Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma.
Hofman IJF, Patchett S, van Duin M, Geerdens E, Verbeeck J, Michaux L, Delforge M, Sonneveld P, Johnson AW, De Keersmaecker K. Hofman IJF, et al. Among authors: de keersmaecker k. Haematologica. 2017 Aug;102(8):e317-e320. doi: 10.3324/haematol.2016.162198. Epub 2017 Apr 20. Haematologica. 2017. PMID: 28428269 Free PMC article. No abstract available.
The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling.
Girardi T, Vereecke S, Sulima SO, Khan Y, Fancello L, Briggs JW, Schwab C, de Beeck JO, Verbeeck J, Royaert J, Geerdens E, Vicente C, Bornschein S, Harrison CJ, Meijerink JP, Cools J, Dinman JD, Kampen KR, De Keersmaecker K. Girardi T, et al. Among authors: de keersmaecker k, de beeck jo. Leukemia. 2018 Mar;32(3):809-819. doi: 10.1038/leu.2017.225. Epub 2017 Jul 24. Leukemia. 2018. PMID: 28744013 Free PMC article.
Ribosomal proteins: a novel class of oncogenic drivers.
Sulima SO, De Keersmaecker K. Sulima SO, et al. Among authors: de keersmaecker k. Oncotarget. 2017 Sep 11;8(52):89427-89428. doi: 10.18632/oncotarget.20802. eCollection 2017 Oct 27. Oncotarget. 2017. PMID: 29163758 Free PMC article. No abstract available.
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: de keersmaecker k. Leukemia. 2019 Feb;33(2):319-332. doi: 10.1038/s41375-018-0176-z. Epub 2018 Jun 21. Leukemia. 2019. PMID: 29930300 Free PMC article.
Rise of the specialized onco-ribosomes.
Kampen KR, Sulima SO, De Keersmaecker K. Kampen KR, et al. Among authors: de keersmaecker k. Oncotarget. 2018 Oct 16;9(81):35205-35206. doi: 10.18632/oncotarget.26231. eCollection 2018 Oct 16. Oncotarget. 2018. PMID: 30443288 Free PMC article. No abstract available.
82 results