Mullan LA - Search Results

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Increased intracellular proteolysis reduces disease severity in an ER stress-associated dwarfism.

Mullan LA, Mularczyk EJ, Kung LH, Forouhan M, Wragg JM, Goodacre R, Bateman JF, Swanton E, Briggs MD, Boot-Handford RP. Mullan LA, et al. J Clin Invest. 2017 Oct 2;127(10):3861-3865. doi: 10.1172/JCI93094. Epub 2017 Sep 18. J Clin Invest. 2017. PMID: 28920921 Free PMC article.

Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases.

Hartley CL, Edwards S, Mullan L, Bell PA, Fresquet M, Boot-Handford RP, Briggs MD. Hartley CL, et al. Hum Mol Genet. 2013 Dec 20;22(25):5262-75. doi: 10.1093/hmg/ddt383. Epub 2013 Aug 15. Hum Mol Genet. 2013. PMID: 23956175 Free PMC article.

XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease.

Cameron TL, Bell KM, Gresshoff IL, Sampurno L, Mullan L, Ermann J, Glimcher LH, Boot-Handford RP, Bateman JF. Cameron TL, et al. PLoS Genet. 2015 Sep 15;11(9):e1005505. doi: 10.1371/journal.pgen.1005505. eCollection 2015 Sep. PLoS Genet. 2015. PMID: 26372225 Free PMC article.

Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis.

Kung LHW, Mullan L, Soul J, Wang P, Mori K, Bateman JF, Briggs MD, Boot-Handford RP. Kung LHW, et al. Arthritis Res Ther. 2019 Sep 11;21(1):206. doi: 10.1186/s13075-019-1988-6. Arthritis Res Ther. 2019. PMID: 31511053 Free PMC article.

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