Melatonin-mediated upregulation of GLUT1 blocks exit from pluripotency by increasing the uptake of oxidized vitamin C in mouse embryonic stem cells.
Wu H, Song C, Zhang J, Zhao J, Fu B, Mao T, Zhang Y.
Wu H, et al. Among authors: fu b.
FASEB J. 2017 Apr;31(4):1731-1743. doi: 10.1096/fj.201601085R. Epub 2017 Jan 9.
FASEB J. 2017.
PMID: 28069827
Our findings provide a theoretical basis for application of melatonin in research on ESCs and iPSCs and for further investigation of the effect of combinatorial compounds on cell reprogramming.-Wu, H., Song, C., Zhang, J., Zhao, J., Fu, B., Mao, T., Zhang, Y. Melato …
Our findings provide a theoretical basis for application of melatonin in research on ESCs and iPSCs and for further investigation of the eff …