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Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis.
Georgiadis P, Liampa I, Hebels DG, Krauskopf J, Chatziioannou A, Valavanis I, de Kok TMCM, Kleinjans JCS, Bergdahl IA, Melin B, Spaeth F, Palli D, Vermeulen RCH, Vlaanderen J, Chadeau-Hyam M, Vineis P, Kyrtopoulos SA; EnviroGenomarkers consortium. Georgiadis P, et al. Among authors: spaeth f. BMC Genomics. 2017 Sep 13;18(1):728. doi: 10.1186/s12864-017-4117-4. BMC Genomics. 2017. PMID: 28903739 Free PMC article.
DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia.
Georgiadis P, Gavriil M, Rantakokko P, Ladoukakis E, Botsivali M, Kelly RS, Bergdahl IA, Kiviranta H, Vermeulen RCH, Spaeth F, Hebbels DGAJ, Kleinjans JCS, de Kok TMCM, Palli D, Vineis P, Kyrtopoulos SA; EnviroGenomarkers consortium. Georgiadis P, et al. Among authors: spaeth f. Environ Int. 2019 May;126:24-36. doi: 10.1016/j.envint.2019.01.068. Epub 2019 Feb 15. Environ Int. 2019. PMID: 30776747 Free PMC article.
Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study.
Naudin S, Solans Margalef M, Saberi Hosnijeh F, Nieters A, Kyrø C, Tjønneland A, Dahm CC, Overvad K, Mahamat-Saleh Y, Besson C, Boutron-Ruault MC, Kühn T, Canzian F, Schulze MB, Peppa E, Karakatsani A, Trichopoulou A, Sieri S, Masala G, Panico S, Tumino R, Ricceri F, Chen SLF, Barroso LL, Huerta JM, Sánchez MJ, Ardanaz E, Menéndez V, Amiano Exezarreta P, Spaeth F, Jerkeman M, Jirstom K, Schmidt JA, Aune D, Weiderpass E, Riboli E, Vermeulen R, Casabonne D, Gunter M, Brennan P, Ferrari P. Naudin S, et al. Among authors: spaeth f. Int J Cancer. 2020 Sep 15;147(6):1649-1656. doi: 10.1002/ijc.32977. Epub 2020 Mar 30. Int J Cancer. 2020. PMID: 32176325 Free article.