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Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.
de Vera IMS, Zheng J, Novick S, Shang J, Hughes TS, Brust R, Munoz-Tello P, Gardner WJ Jr, Marciano DP, Kong X, Griffin PR, Kojetin DJ. de Vera IMS, et al. Among authors: brust r. Structure. 2017 Oct 3;25(10):1506-1518.e4. doi: 10.1016/j.str.2017.07.019. Epub 2017 Sep 7. Structure. 2017. PMID: 28890360 Free PMC article.
Quantitative structural assessment of graded receptor agonism.
Shang J, Brust R, Griffin PR, Kamenecka TM, Kojetin DJ. Shang J, et al. Among authors: brust r. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22179-22188. doi: 10.1073/pnas.1909016116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611383 Free PMC article.
Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy.
Hughes TS, Shang J, Brust R, de Vera IMS, Fuhrmann J, Ruiz C, Cameron MD, Kamenecka TM, Kojetin DJ. Hughes TS, et al. Among authors: brust r. J Med Chem. 2016 Nov 23;59(22):10335-10341. doi: 10.1021/acs.jmedchem.6b01340. Epub 2016 Nov 4. J Med Chem. 2016. PMID: 27783520 Free PMC article.
83 results