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Antipsychotic activity of substituted gamma-carbolines.
Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1987 Oct;30(10):1818-23. doi: 10.1021/jm00393a023. J Med Chem. 1987. PMID: 2888898
Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents.
Abou-Gharbia MA, Childers WE Jr, Fletcher H, McGaughey G, Patel U, Webb MB, Yardley J, Andree T, Boast C, Kucharik RJ Jr, Marquis K, Morris H, Scerni R, Moyer JA. Abou-Gharbia MA, et al. Among authors: moyer ja. J Med Chem. 1999 Dec 16;42(25):5077-94. doi: 10.1021/jm9806704. J Med Chem. 1999. PMID: 10602693
Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere.
Kinney WA, Abou-Gharbia M, Garrison DT, Schmid J, Kowal DM, Bramlett DR, Miller TL, Tasse RP, Zaleska MM, Moyer JA. Kinney WA, et al. Among authors: moyer ja. J Med Chem. 1998 Jan 15;41(2):236-46. doi: 10.1021/jm970504g. J Med Chem. 1998. PMID: 9457246
48 results