Brodt P - Search Results

1

The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells.

Fernandez MC, Rayes R, Ham B, Wang N, Bourdeau F, Milette S, Lllemann M, Bird N, Majeed A, Xu J, Kisselova T, Brodt P. Fernandez MC, et al. Among authors: brodt p. Oncotarget. 2016 Oct 12;8(32):52281-52293. doi: 10.18632/oncotarget.12595. eCollection 2017 Aug 8. Oncotarget. 2016. PMID: 28881729 Free PMC article.

2

Characterization of the host proinflammatory response to tumor cells during the initial stages of liver metastasis.

Khatib AM, Auguste P, Fallavollita L, Wang N, Samani A, Kontogiannea M, Meterissian S, Brodt P. Khatib AM, et al. Among authors: brodt p. Am J Pathol. 2005 Sep;167(3):749-59. doi: 10.1016/S0002-9440(10)62048-2. Am J Pathol. 2005. PMID: 16127154 Free PMC article.

3

The secretory leukocyte protease inhibitor is a type 1 insulin-like growth factor receptor-regulated protein that protects against liver metastasis by attenuating the host proinflammatory response.

Wang N, Thuraisingam T, Fallavollita L, Ding A, Radzioch D, Brodt P. Wang N, et al. Among authors: brodt p. Cancer Res. 2006 Mar 15;66(6):3062-70. doi: 10.1158/0008-5472.CAN-05-2638. Cancer Res. 2006. PMID: 16540655

4

The host inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation.

Auguste P, Fallavollita L, Wang N, Burnier J, Bikfalvi A, Brodt P. Auguste P, et al. Among authors: brodt p. Am J Pathol. 2007 May;170(5):1781-92. doi: 10.2353/ajpath.2007.060886. Am J Pathol. 2007. PMID: 17456781 Free PMC article.

5

Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases.

Wang N, Fallavollita L, Nguyen L, Burnier J, Rafei M, Galipeau J, Yakar S, Brodt P. Wang N, et al. Among authors: brodt p. Mol Ther. 2009 Jul;17(7):1241-9. doi: 10.1038/mt.2009.82. Epub 2009 Apr 14. Mol Ther. 2009. PMID: 19367255 Free PMC article.

6

The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.

Li S, Zhang D, Yang L, Burnier JV, Wang N, Lin R, Lee ER, Glazer RI, Brodt P. Li S, et al. Among authors: brodt p. Mol Endocrinol. 2009 Dec;23(12):2013-25. doi: 10.1210/me.2009-0197. Epub 2009 Oct 23. Mol Endocrinol. 2009. PMID: 19855090 Free PMC article.

7

Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis.

Burnier JV, Wang N, Michel RP, Hassanain M, Li S, Lu Y, Metrakos P, Antecka E, Burnier MN, Ponton A, Gallinger S, Brodt P. Burnier JV, et al. Among authors: brodt p. Oncogene. 2011 Sep 1;30(35):3766-83. doi: 10.1038/onc.2011.89. Epub 2011 Apr 11. Oncogene. 2011. PMID: 21478904

8

Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling.

Li S, Wang N, Brodt P. Li S, et al. Among authors: brodt p. Cancer Res. 2012 Feb 15;72(4):865-75. doi: 10.1158/0008-5472.CAN-11-1357. Epub 2011 Dec 22. Cancer Res. 2012. PMID: 22194466

9

Sustained production of a soluble IGF-I receptor by gutless adenovirus-transduced host cells protects from tumor growth in the liver.

Wang N, Lu Y, Pinard M, Pilotte A, Gilbert R, Massie B, Brodt P. Wang N, et al. Among authors: brodt p. Cancer Gene Ther. 2013 Apr;20(4):229-36. doi: 10.1038/cgt.2013.10. Epub 2013 Mar 8. Cancer Gene Ther. 2013. PMID: 23470563

10

The multifaceted role of the microenvironment in liver metastasis: biology and clinical implications.

Van den Eynden GG, Majeed AW, Illemann M, Vermeulen PB, Bird NC, Høyer-Hansen G, Eefsen RL, Reynolds AR, Brodt P. Van den Eynden GG, et al. Among authors: brodt p. Cancer Res. 2013 Apr 1;73(7):2031-43. doi: 10.1158/0008-5472.CAN-12-3931. Epub 2013 Mar 27. Cancer Res. 2013. PMID: 23536564 Review.

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