Ma X - Search Results

1

Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.

Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z. Song Y, et al. Among authors: ma x. Cell Biol Int. 2017 Dec;41(12):1367-1378. doi: 10.1002/cbin.10868. Epub 2017 Sep 20. Cell Biol Int. 2017. PMID: 28880428

2

O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.

Liao H, Bao X, Zhu J, Qu J, Sun Y, Ma X, Wang E, Guo X, Kang Q, Zhen Y. Liao H, et al. Among authors: ma x. Chem Biol Interact. 2015 Dec 5;242:91-8. doi: 10.1016/j.cbi.2015.09.022. Epub 2015 Sep 28. Chem Biol Interact. 2015. PMID: 26415619

3

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Song Z, Jin Y, Ge Y, Wang C, Zhang J, Tang Z, Peng J, Liu K, Li Y, Ma X. Song Z, et al. Among authors: ma x. Bioorg Med Chem. 2016 Nov 1;24(21):5505-5512. doi: 10.1016/j.bmc.2016.09.001. Epub 2016 Sep 3. Bioorg Med Chem. 2016. PMID: 27634676

4

Novel Selective and Potent EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Non-Small Cell Lung Cancer.

Li Y, Song Z, Jin Y, Tang Z, Kang J, Ma X. Li Y, et al. Among authors: ma x. Molecules. 2016 Nov 2;21(11):1462. doi: 10.3390/molecules21111462. Molecules. 2016. PMID: 27827863 Free PMC article.

5

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Zhao D, Huang S, Qu M, Wang C, Liu Z, Li Z, Peng J, Liu K, Li Y, Ma X, Shu X. Zhao D, et al. Among authors: ma x. Eur J Med Chem. 2017 Jan 27;126:444-455. doi: 10.1016/j.ejmech.2016.11.047. Epub 2016 Nov 23. Eur J Med Chem. 2017. PMID: 27912175

6

Discovery of Novel Bruton's Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold.

Ge Y, Jin Y, Wang C, Zhang J, Tang Z, Peng J, Liu K, Li Y, Zhou Y, Ma X. Ge Y, et al. Among authors: ma x. ACS Med Chem Lett. 2016 Sep 21;7(12):1050-1055. doi: 10.1021/acsmedchemlett.6b00235. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994736 Free PMC article.

7

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.

Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K. Xue C, et al. Among authors: ma x. Oncotarget. 2017 Jan 31;8(5):8622-8632. doi: 10.18632/oncotarget.14373. Oncotarget. 2017. PMID: 28052008 Free PMC article.

8

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation.

Zhang Y, Xu Y, Qi Y, Xu L, Song S, Yin L, Tao X, Zhen Y, Han X, Ma X, Liu K, Peng J. Zhang Y, et al. Among authors: ma x. Toxicology. 2017 Mar 1;378:53-64. doi: 10.1016/j.tox.2017.01.007. Epub 2017 Jan 9. Toxicology. 2017. PMID: 28082111

9

C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFR^T790M mutant.

Song A, Zhang J, Ge Y, Wang C, Meng Q, Tang Z, Peng J, Liu K, Li Y, Ma X. Song A, et al. Among authors: ma x. Bioorg Med Chem. 2017 May 15;25(10):2724-2729. doi: 10.1016/j.bmc.2017.03.032. Epub 2017 Mar 18. Bioorg Med Chem. 2017. PMID: 28385595

10

Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

Liu H, Qu M, Xu L, Han X, Wang C, Shu X, Yao J, Liu K, Peng J, Li Y, Ma X. Liu H, et al. Among authors: ma x. Eur J Med Chem. 2017 Jul 28;135:60-69. doi: 10.1016/j.ejmech.2017.04.037. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28432946

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