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Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy.
Liu R, Lee J, Kim BS, Wang Q, Buxton SK, Balasubramanyam N, Kim JJ, Dong J, Zhang A, Li S, Gupte AA, Hamilton DJ, Martin JF, Rodney GG, Coarfa C, Wehrens XH, Yechoor VK, Moulik M. Liu R, et al. Among authors: wehrens xh. JCI Insight. 2017 Sep 7;2(17):e93343. doi: 10.1172/jci.insight.93343. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878117 Free PMC article.
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
van Oort RJ, McCauley MD, Dixit SS, Pereira L, Yang Y, Respress JL, Wang Q, De Almeida AC, Skapura DG, Anderson ME, Bers DM, Wehrens XH. van Oort RJ, et al. Among authors: wehrens xh. Circulation. 2010 Dec 21;122(25):2669-79. doi: 10.1161/CIRCULATIONAHA.110.982298. Epub 2010 Nov 15. Circulation. 2010. PMID: 21098440 Free PMC article.
Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.
Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XHT. Li N, et al. Circulation. 2014 Mar 25;129(12):1276-1285. doi: 10.1161/CIRCULATIONAHA.113.006611. Epub 2014 Jan 7. Circulation. 2014. PMID: 24398018 Free PMC article.
289 results