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Heparin Increases Food Intake through AgRP Neurons.
Zhu C, Xu P, He Y, Yuan Y, Wang T, Cai X, Yu L, Yang L, Wu J, Wang L, Zhu X, Wang S, Gao P, Xi Q, Zhang Y, Xu Y, Jiang Q, Shu G. Zhu C, et al. Among authors: cai x. Cell Rep. 2017 Sep 5;20(10):2455-2467. doi: 10.1016/j.celrep.2017.08.049. Cell Rep. 2017. PMID: 28877477 Free PMC article.
α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway.
Cai X, Yuan Y, Liao Z, Xing K, Zhu C, Xu Y, Yu L, Wang L, Wang S, Zhu X, Gao P, Zhang Y, Jiang Q, Xu P, Shu G. Cai X, et al. FASEB J. 2018 Jan;32(1):488-499. doi: 10.1096/fj.201700670R. Epub 2017 Sep 22. FASEB J. 2018. PMID: 28939592 Free PMC article.
These findings not only provide a molecular basis for the potential use of exercise-generated metabolite AKG in muscle atrophy treatment, but also identify PHD3 as a potential target for the development of therapies for muscle wasting.-Cai, X., Yuan, Y., Liao, Z., X …
These findings not only provide a molecular basis for the potential use of exercise-generated metabolite AKG in muscle atrophy treatment, bu …
Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling.
Wang T, Xu YQ, Yuan YX, Xu PW, Zhang C, Li F, Wang LN, Yin C, Zhang L, Cai XC, Zhu CJ, Xu JR, Liang BQ, Schaul S, Xie PP, Yue D, Liao ZR, Yu LL, Luo L, Zhou G, Yang JP, He ZH, Du M, Zhou YP, Deng BC, Wang SB, Gao P, Zhu XT, Xi QY, Zhang YL, Shu G, Jiang QY. Wang T, et al. EMBO Rep. 2019 Sep;20(9):e47892. doi: 10.15252/embr.201947892. Epub 2019 Jul 18. EMBO Rep. 2019. PMID: 31318145 Free PMC article.
Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation.
Yuan Y, Xu P, Jiang Q, Cai X, Wang T, Peng W, Sun J, Zhu C, Zhang C, Yue D, He Z, Yang J, Zeng Y, Du M, Zhang F, Ibrahimi L, Schaul S, Jiang Y, Wang J, Sun J, Wang Q, Liu L, Wang S, Wang L, Zhu X, Gao P, Xi Q, Yin C, Li F, Xu G, Zhang Y, Shu G. Yuan Y, et al. Among authors: cai x. EMBO J. 2020 Apr 1;39(7):e103304. doi: 10.15252/embj.2019103304. Epub 2020 Feb 27. EMBO J. 2020. PMID: 32104923 Free PMC article.
Succinate induces skeletal muscle fiber remodeling via SUCNR1 signaling.
Wang T, Xu YQ, Yuan YX, Xu PW, Zhang C, Li F, Wang LN, Yin C, Zhang L, Cai XC, Zhu CJ, Xu JR, Liang BQ, Schaul S, Xie PP, Yue D, Liao ZR, Yu LL, Luo L, Zhou G, Yang JP, He ZH, Du M, Zhou YP, Deng BC, Wang SB, Gao P, Zhu XT, Xi QY, Zhang YL, Shu G, Jiang QY. Wang T, et al. EMBO Rep. 2020 May 6;21(5):e50461. doi: 10.15252/embr.202050461. EMBO Rep. 2020. PMID: 32374525 Free PMC article.
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