Karasik A - Search Results

1

Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P.

Klemm BP, Karasik A, Kaitany KJ, Shanmuganathan A, Henley MJ, Thelen AZ, Dewar AJL, Jackson ND, Koutmos M, Fierke CA. Klemm BP, et al. Among authors: karasik a. RNA. 2017 Dec;23(12):1860-1873. doi: 10.1261/rna.061457.117. Epub 2017 Sep 5. RNA. 2017. PMID: 28874505 Free PMC article.

2

Nuclear Protein-Only Ribonuclease P2 Structure and Biochemical Characterization Provide Insight into the Conserved Properties of tRNA 5' End Processing Enzymes.

Karasik A, Shanmuganathan A, Howard MJ, Fierke CA, Koutmos M. Karasik A, et al. J Mol Biol. 2016 Jan 16;428(1):26-40. doi: 10.1016/j.jmb.2015.11.025. Epub 2015 Dec 3. J Mol Biol. 2016. PMID: 26655022 Free PMC article.

3

Differential substrate recognition by isozymes of plant protein-only Ribonuclease P.

Howard MJ, Karasik A, Klemm BP, Mei C, Shanmuganathan A, Fierke CA, Koutmos M. Howard MJ, et al. Among authors: karasik a. RNA. 2016 May;22(5):782-92. doi: 10.1261/rna.055541.115. Epub 2016 Mar 10. RNA. 2016. PMID: 26966150 Free PMC article.

4

Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila.

Sen A, Karasik A, Shanmuganathan A, Mirkovic E, Koutmos M, Cox RT. Sen A, et al. Among authors: karasik a. Nucleic Acids Res. 2016 Jul 27;44(13):6409-22. doi: 10.1093/nar/gkw338. Epub 2016 Apr 30. Nucleic Acids Res. 2016. PMID: 27131785 Free PMC article.

5

Antivitamin B₁₂ Inhibition of the Human B₁₂ -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate.

Ruetz M, Shanmuganathan A, Gherasim C, Karasik A, Salchner R, Kieninger C, Wurst K, Banerjee R, Koutmos M, Kräutler B. Ruetz M, et al. Among authors: karasik a. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7387-7392. doi: 10.1002/anie.201701583. Epub 2017 May 23. Angew Chem Int Ed Engl. 2017. PMID: 28544088 Free PMC article.

6

Interplay between substrate recognition, 5' end tRNA processing and methylation activity of human mitochondrial RNase P.

Karasik A, Fierke CA, Koutmos M. Karasik A, et al. RNA. 2019 Dec;25(12):1646-1660. doi: 10.1261/rna.069310.118. Epub 2019 Aug 27. RNA. 2019. PMID: 31455609 Free PMC article.

7

Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation, and tRNA processing by mtRNase P.

Karasik A, Wilhelm CA, Fierke CA, Koutmos M. Karasik A, et al. RNA. 2021 Apr;27(4):420-432. doi: 10.1261/rna.077198.120. Epub 2020 Dec 30. RNA. 2021. PMID: 33380464 Free PMC article.

8

Gambogic acid and juglone inhibit RNase P through distinct mechanisms.

Wu Meyers N, Karasik A, Kaitany K, Fierke CA, Koutmos M. Wu Meyers N, et al. Among authors: karasik a. J Biol Chem. 2022 Dec;298(12):102683. doi: 10.1016/j.jbc.2022.102683. Epub 2022 Nov 9. J Biol Chem. 2022. PMID: 36370850 Free PMC article.

9

The Unusual Role of Ribonuclease L in Innate Immunity.

Karasik A, Guydosh NR. Karasik A, et al. Wiley Interdiscip Rev RNA. 2024 Nov-Dec;15(6):e1878. doi: 10.1002/wrna.1878. Wiley Interdiscip Rev RNA. 2024. PMID: 39727035 Free PMC article. Review.

10

Activation of the antiviral factor RNase L triggers translation of non-coding mRNA sequences.

Karasik A, Jones GD, DePass AV, Guydosh NR. Karasik A, et al. Nucleic Acids Res. 2021 Jun 21;49(11):6007-6026. doi: 10.1093/nar/gkab036. Nucleic Acids Res. 2021. PMID: 33556964 Free PMC article.

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