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Page 1
Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.
Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Tulloch LB, Smith TK. Florence GJ, et al. Among authors: menzies sk. ChemMedChem. 2014 Nov;9(11):2548-56. doi: 10.1002/cmdc.201402272. Epub 2014 Aug 21. ChemMedChem. 2014. PMID: 25145275 Free PMC article.
Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.
Fraser AL, Menzies SK, King EFB, Tulloch LB, Gould ER, Zacharova MK, Smith TK, Florence GJ. Fraser AL, et al. Among authors: menzies sk. ACS Infect Dis. 2018 Apr 13;4(4):560-567. doi: 10.1021/acsinfecdis.7b00187. Epub 2018 Jan 19. ACS Infect Dis. 2018. PMID: 29313667
Direct and indirect approaches to identify drug modes of action.
Tulloch LB, Menzies SK, Coron RP, Roberts MD, Florence GJ, Smith TK. Tulloch LB, et al. Among authors: menzies sk. IUBMB Life. 2018 Jan;70(1):9-22. doi: 10.1002/iub.1697. Epub 2017 Dec 6. IUBMB Life. 2018. PMID: 29210173 Free article. Review.
Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase.
Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ. Zacharova MK, et al. Among authors: menzies sk. European J Org Chem. 2019 Sep 1;2019(31-32):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29. European J Org Chem. 2019. PMID: 31598093 Free PMC article.
Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing.
Menzies SK, Litschka-Koen T, Edge RJ, Alsolaiss J, Crittenden E, Hall SR, Westhorpe A, Thomas B, Murray J, Shongwe N, Padidar S, Lalloo DG, Casewell NR, Pons J, Harrison RA. Menzies SK, et al. PLoS Negl Trop Dis. 2022 Sep 15;16(9):e0010496. doi: 10.1371/journal.pntd.0010496. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36108067 Free PMC article.
An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management.
Ainsworth S, Menzies SK, Casewell NR, Harrison RA. Ainsworth S, et al. Among authors: menzies sk. PLoS Negl Trop Dis. 2020 Aug 20;14(8):e0008579. doi: 10.1371/journal.pntd.0008579. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32817682 Free PMC article.
26 results