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Page 1
Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection.
Zambalde ÉP, Dias TL, Maktura GC, Amorim MR, Brenha B, Santos LN, Buscaratti L, Elston JGA, Mancini MCS, Pavan ICB, Toledo-Teixeira DA, Bispo-Dos-Santos K, Parise PL, Morelli AP, Silva LGSD, Castro ÍMS, Saccon TD, Mori MA, Granja F, Nakaya HI, Proenca-Modena JL, Marques-Souza H, Simabuco FM. Zambalde ÉP, et al. Among authors: simabuco fm. Curr Issues Mol Biol. 2022 Dec 31;45(1):327-336. doi: 10.3390/cimb45010023. Curr Issues Mol Biol. 2022. PMID: 36661509 Free PMC article.
Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni).
Dematei A, Costa SR, Moreira DC, Barbosa EA, Friaça Albuquerque LF, Vasconcelos AG, Nascimento T, Silva PC, Silva-Carvalho AÉ, Saldanha-Araújo F, Silva Mancini MC, Saboia Ponte LG, Neves Bezerra RM, Simabuco FM, Batagin-Neto A, Brand G, Borges TKS, Eaton P, Leite JRSA. Dematei A, et al. Among authors: simabuco fm. J Nat Prod. 2022 Dec 23;85(12):2695-2705. doi: 10.1021/acs.jnatprod.2c00304. Epub 2022 Dec 12. J Nat Prod. 2022. PMID: 36508333
The S6K protein family in health and disease.
Tavares MR, Pavan IC, Amaral CL, Meneguello L, Luchessi AD, Simabuco FM. Tavares MR, et al. Among authors: simabuco fm. Life Sci. 2015 Jun 15;131:1-10. doi: 10.1016/j.lfs.2015.03.001. Epub 2015 Mar 26. Life Sci. 2015. PMID: 25818187 Review.
Different interactomes for p70-S6K1 and p54-S6K2 revealed by proteomic analysis.
Pavan IC, Yokoo S, Granato DC, Meneguello L, Carnielli CM, Tavares MR, do Amaral CL, de Freitas LB, Paes Leme AF, Luchessi AD, Simabuco FM. Pavan IC, et al. Among authors: simabuco fm. Proteomics. 2016 Oct;16(20):2650-2666. doi: 10.1002/pmic.201500249. Epub 2016 Sep 12. Proteomics. 2016. PMID: 27493124
Cdc2-like kinase 2 in the hypothalamus is necessary to maintain energy homeostasis.
Quaresma PG, Weissmann L, Zanotto TM, Santos AC, de Matos AH, Furigo IC, Simabuco FM, Donato J Jr, Bittencourt JC, Lopes-Cendes I, Prada PO. Quaresma PG, et al. Among authors: simabuco fm. Int J Obes (Lond). 2017 Feb;41(2):268-278. doi: 10.1038/ijo.2016.174. Epub 2016 Oct 13. Int J Obes (Lond). 2017. PMID: 27733761
Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice.
Pinto AP, da Rocha AL, Kohama EB, Gaspar RC, Simabuco FM, Frantz FG, de Moura LP, Pauli JR, Cintra DE, Ropelle ER, de Freitas EC, da Silva ASR. Pinto AP, et al. Among authors: simabuco fm. J Endocrinol. 2019 Feb 1;240(2):181-193. doi: 10.1530/JOE-18-0404. J Endocrinol. 2019. PMID: 30400033
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