Ma L - Search Results

1

Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.

Niu L, Wang Y, Wang C, Wang Y, Jiang X, Ma L, Wu C, Yu Y, Chen Q. Niu L, et al. Among authors: ma l. Biochem Biophys Res Commun. 2017 Nov 4;493(1):718-722. doi: 10.1016/j.bbrc.2017.08.125. Epub 2017 Aug 30. Biochem Biophys Res Commun. 2017. PMID: 28864414

2

Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.

Zhang Z, Wang C, Ma L, Jiang X, Wu C, Wang Y, Jiang Y, Zheng W, Yang Y, Ma Y, Yang J. Zhang Z, et al. Among authors: ma l, ma y. Biochem Biophys Res Commun. 2019 Apr 2;511(2):381-386. doi: 10.1016/j.bbrc.2019.02.064. Epub 2019 Feb 22. Biochem Biophys Res Commun. 2019. PMID: 30803758

3

Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.

Ma M, Ding Z, Wang S, Ma L, Wang Y, Zhong L, Li Z, Yang J, Li W. Ma M, et al. Among authors: ma l. Bioorg Med Chem. 2019 May 1;27(9):1836-1844. doi: 10.1016/j.bmc.2019.03.035. Epub 2019 Mar 20. Bioorg Med Chem. 2019. PMID: 30910474

4

Discovery of Novel Benzimidazole and Indazole Analogues as Tubulin Polymerization Inhibitors with Potent Anticancer Activities.

Ren Y, Wang Y, Li G, Zhang Z, Ma L, Cheng B, Chen J. Ren Y, et al. Among authors: ma l. J Med Chem. 2021 Apr 22;64(8):4498-4515. doi: 10.1021/acs.jmedchem.0c01837. Epub 2021 Mar 31. J Med Chem. 2021. PMID: 33788562

5

X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor.

Banerjee S, Mahmud F, Deng S, Ma L, Yun MK, Fakayode SO, Arnst KE, Yang L, Chen H, Wu Z, Lukka PB, Parmar K, Meibohm B, White SW, Wang Y, Li W, Miller DD. Banerjee S, et al. Among authors: ma l. J Med Chem. 2021 Sep 9;64(17):13072-13095. doi: 10.1021/acs.jmedchem.1c01202. Epub 2021 Aug 18. J Med Chem. 2021. PMID: 34406768 Free PMC article.

6

Structural insights into targeting of the colchicine binding site by ELR510444 and parbendazole to achieve rational drug design.

Lei JH, Ma LL, Xian JH, Chen H, Zhou JJ, Chen H, Lei Q, Li YY, Wang YY, Wang YX. Lei JH, et al. RSC Adv. 2021 May 25;11(31):18938-18944. doi: 10.1039/d1ra01173a. eCollection 2021 May 24. RSC Adv. 2021. PMID: 35478655 Free PMC article.

7

Structural insight into SSE15206 in complex with tubulin provides a rational design for pyrazolinethioamides as tubulin polymerization inhibitors.

Ma L, Lei J, Chen H, Huang R, Su T, Feng J, Sun Q. Ma L, et al. Future Med Chem. 2022 Jun;14(11):785-794. doi: 10.4155/fmc-2021-0124. Epub 2022 May 4. Future Med Chem. 2022. PMID: 35506429

8

The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations.

Xia Z, Huang R, Zhou X, Chai Y, Chen H, Ma L, Yu Q, Li Y, Li W, He Y. Xia Z, et al. Among authors: ma l. Eur J Med Chem. 2021 Nov 15;224:113711. doi: 10.1016/j.ejmech.2021.113711. Epub 2021 Jul 21. Eur J Med Chem. 2021. PMID: 34315040

9

Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance.

Xiao H, Zheng Y, Ma L, Tian L, Sun Q. Xiao H, et al. Among authors: ma l. Front Pharmacol. 2021 Apr 19;12:648407. doi: 10.3389/fphar.2021.648407. eCollection 2021. Front Pharmacol. 2021. PMID: 33953682 Free PMC article. Review.

10

SARS-CoV-2 SUD2 and Nsp5 Conspire to Boost Apoptosis of Respiratory Epithelial Cells via an Augmented Interaction with the G-Quadruplex of BclII.

Li Y, Yu Q, Huang R, Chen H, Ren H, Ma L, He Y, Li W. Li Y, et al. Among authors: ma l. mBio. 2023 Apr 25;14(2):e0335922. doi: 10.1128/mbio.03359-22. Epub 2023 Feb 28. mBio. 2023. PMID: 36853058 Free PMC article.

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