Jiang X - Search Results

1

Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.

Niu L, Wang Y, Wang C, Wang Y, Jiang X, Ma L, Wu C, Yu Y, Chen Q. Niu L, et al. Among authors: jiang x. Biochem Biophys Res Commun. 2017 Nov 4;493(1):718-722. doi: 10.1016/j.bbrc.2017.08.125. Epub 2017 Aug 30. Biochem Biophys Res Commun. 2017. PMID: 28864414

2

Preparation and characterization of a high-affinity monoclonal antibody against human epididymis protein-4.

Shen Y, Wang Y, Jiang X, Lu L, Wang C, Luo W, Zhang Y, Li P, Du Z, Dai T, Wu C, Fang A, Yao Y, Peng Q, Yang J. Shen Y, et al. Among authors: jiang x. Protein Expr Purif. 2018 Jan;141:44-51. doi: 10.1016/j.pep.2017.09.005. Epub 2017 Sep 18. Protein Expr Purif. 2018. PMID: 28928083

3

Therapeutic potential of an anti-HER2 single chain antibody-DM1 conjugates for the treatment of HER2-positive cancer.

Zhang H, Wang Y, Wu Y, Jiang X, Tao Y, Yao Y, Peng Y, Chen X, Fu Y, Yu L, Wang R, Lai Q, Lai W, Li W, Kang Y, Yi S, Lu Y, Gou L, Wu M, Yang J. Zhang H, et al. Among authors: jiang x. Signal Transduct Target Ther. 2017 May 19;2:17015. doi: 10.1038/sigtrans.2017.15. eCollection 2017. Signal Transduct Target Ther. 2017. PMID: 29263918 Free PMC article.

4

Expression of 5T4 extracellular domain fusion protein and preparation of anti-5T4 monoclonal antibody with high affinity and internalization efficiency.

Wang R, Lai Q, Lu Y, Zhou Y, Tang L, Tao Y, Yao Y, Yu L, Liu Y, Wang Y, Zhang R, Jiang X, Gou L, Yang J. Wang R, et al. Among authors: jiang x. Protein Expr Purif. 2019 Jun;158:51-58. doi: 10.1016/j.pep.2018.07.003. Epub 2018 Jul 6. Protein Expr Purif. 2019. PMID: 29981846

5

Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.

Zhang Z, Wang C, Ma L, Jiang X, Wu C, Wang Y, Jiang Y, Zheng W, Yang Y, Ma Y, Yang J. Zhang Z, et al. Among authors: jiang x, jiang y. Biochem Biophys Res Commun. 2019 Apr 2;511(2):381-386. doi: 10.1016/j.bbrc.2019.02.064. Epub 2019 Feb 22. Biochem Biophys Res Commun. 2019. PMID: 30803758

6

Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma.

Tao Y, Wang R, Lai Q, Wu M, Wang Y, Jiang X, Zeng L, Zhou S, Li Z, Yang T, Yao Y, Wu Y, Yu L, Fu Y, Lai W, Peng Y, Lu Y, Zhang Z, Guo C, Zhang G, Gou L, Yang J. Tao Y, et al. Among authors: jiang x. Mol Oncol. 2019 Sep;13(9):1855-1873. doi: 10.1002/1878-0261.12520. Epub 2019 Jul 22. Mol Oncol. 2019. PMID: 31116512 Free PMC article.

7

Cryptophycin-55/52 based antibody-drug conjugates: Synthesis, efficacy, and mode of action studies.

Lai Q, Wu M, Wang R, Lai W, Tao Y, Lu Y, Wang Y, Yu L, Zhang R, Peng Y, Jiang X, Fu Y, Wang X, Zhang Z, Guo C, Liao W, Zhang Y, Kang T, Chen H, Yao Y, Gou L, Yang J. Lai Q, et al. Among authors: jiang x. Eur J Med Chem. 2020 Aug 1;199:112364. doi: 10.1016/j.ejmech.2020.112364. Epub 2020 Apr 30. Eur J Med Chem. 2020. PMID: 32402935

8

Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma.

Fu Y, Peng Y, Zhao S, Mou J, Zeng L, Jiang X, Yang C, Huang C, Li Y, Lu Y, Wu M, Yang Y, Kong T, Lai Q, Wu Y, Yao Y, Wang Y, Gou L, Yang J. Fu Y, et al. Among authors: jiang x. Front Cell Dev Biol. 2021 Jul 8;9:689727. doi: 10.3389/fcell.2021.689727. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34307367 Free PMC article.

9

Design, Synthesis, and Bioevaluation of a Novel Hybrid Molecular Pyrrolobenzodiazepine-Anthracenecarboxyimide as a Payload for Antibody-Drug Conjugate.

Lai W, Zhao S, Lai Q, Zhou W, Wu M, Jiang X, Wang X, Peng Y, Wei X, Ouyang L, Gou L, Chen H, Wang Y, Yang J. Lai W, et al. Among authors: jiang x. J Med Chem. 2022 Sep 8;65(17):11679-11702. doi: 10.1021/acs.jmedchem.2c00471. Epub 2022 Aug 18. J Med Chem. 2022. PMID: 35982539

10

Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic effects with anti-CTLA-4 therapy.

Peng Y, Fu Y, Liu H, Zhao S, Deng H, Jiang X, Lai Q, Lu Y, Guo C, Zhang G, Luo Y, Wang Y, Gou L, Yang J. Peng Y, et al. Among authors: jiang x. Int J Cancer. 2024 Apr 1;154(7):1285-1297. doi: 10.1002/ijc.34823. Epub 2024 Jan 5. Int J Cancer. 2024. PMID: 38180065

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