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The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Hernández IH, Torres-Peraza J, Santos-Galindo M, Ramos-Morón E, Fernández-Fernández MR, Pérez-Álvarez MJ, Miranda-Vizuete A, Lucas JJ. Hernández IH, et al. Among authors: lucas jj. Acta Neuropathol. 2017 Dec;134(6):839-850. doi: 10.1007/s00401-017-1770-2. Epub 2017 Aug 31. Acta Neuropathol. 2017. PMID: 28861715 Free article.
The ubiquitin-proteasome system in Huntington's disease.
Valera AG, Díaz-Hernández M, Hernández F, Ortega Z, Lucas JJ. Valera AG, et al. Among authors: lucas jj. Neuroscientist. 2005 Dec;11(6):583-94. doi: 10.1177/1073858405280639. Neuroscientist. 2005. PMID: 16282599 Review.
PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.
Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. Among authors: lucas jj. Cell Death Differ. 2010 Feb;17(2):324-35. doi: 10.1038/cdd.2009.127. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745829
Presynaptic dysfunction in Huntington's disease.
Rozas JL, Gómez-Sánchez L, Tomás-Zapico C, Lucas JJ, Fernández-Chacón R. Rozas JL, et al. Among authors: lucas jj. Biochem Soc Trans. 2010 Apr;38(2):488-92. doi: 10.1042/BST0380488. Biochem Soc Trans. 2010. PMID: 20298208 Review.
284 results