O'Shea RD - Search Results

1

SOD1 Mutations Causing Familial Amyotrophic Lateral Sclerosis Induce Toxicity in Astrocytes: Evidence for Bystander Effects in a Continuum of Astrogliosis.

Wallis N, Lau CL, Farg MA, Atkin JD, Beart PM, O'Shea RD. Wallis N, et al. Among authors: o shea rd. Neurochem Res. 2018 Jan;43(1):166-179. doi: 10.1007/s11064-017-2385-7. Epub 2017 Aug 31. Neurochem Res. 2018. PMID: 28861673

2

Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype.

Zagami CJ, O'Shea RD, Lau CL, Cheema SS, Beart PM. Zagami CJ, et al. Neurotox Res. 2005;7(1-2):143-9. doi: 10.1007/BF03033783. Neurotox Res. 2005. PMID: 15639805

3

Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis.

Zagami CJ, Beart PM, Wallis N, Nagley P, O'Shea RD. Zagami CJ, et al. Glia. 2009 Jan 15;57(2):119-35. doi: 10.1002/glia.20739. Glia. 2009. PMID: 18661557

4

Transportable and non-transportable inhibitors of L-glutamate uptake produce astrocytic stellation and increase EAAT2 cell surface expression.

Lau CL, Beart PM, O'Shea RD. Lau CL, et al. Among authors: o shea rd. Neurochem Res. 2010 May;35(5):735-42. doi: 10.1007/s11064-010-0130-6. Epub 2010 Feb 9. Neurochem Res. 2010. PMID: 20143158

5

Combined excitotoxic-oxidative stress and the concept of non-cell autonomous pathology of ALS: insights into motoneuron axonopathy and astrogliosis.

Wallis N, Zagami CJ, Beart PM, O'Shea RD. Wallis N, et al. Among authors: o shea rd. Neurochem Int. 2012 Sep;61(4):523-30. doi: 10.1016/j.neuint.2012.02.026. Epub 2012 Mar 6. Neurochem Int. 2012. PMID: 22421531

6

Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: new evidence on substrates and blockers in excitotoxicity.

O'Shea RD, Fodera MV, Apricó K, Dehnes Y, Danbolt NC, Crawford D, Beart PM. O'Shea RD, et al. Neurochem Res. 2002 Feb;27(1-2):5-13. doi: 10.1023/a:1014813518604. Neurochem Res. 2002. PMID: 11926276

7

Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1.

O'Shea RD, Lau CL, Farso MC, Diwakarla S, Zagami CJ, Svendsen BB, Feeney SJ, Callaway JK, Jones NM, Pow DV, Danbolt NC, Jarrott B, Beart PM. O'Shea RD, et al. Neurochem Int. 2006 May-Jun;48(6-7):604-10. doi: 10.1016/j.neuint.2005.12.028. Epub 2006 Mar 10. Neurochem Int. 2006. PMID: 16530295

8

Evidence group I mGluR drugs modulate the activation profile of lipopolysaccharide-exposed microglia in culture.

Farso MC, O'Shea RD, Beart PM. Farso MC, et al. Neurochem Res. 2009 Oct;34(10):1721-8. doi: 10.1007/s11064-009-9999-3. Epub 2009 May 29. Neurochem Res. 2009. PMID: 19479374

9

Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses.

Lau CL, Perreau VM, Chen MJ, Cate HS, Merlo D, Cheung NS, O'Shea RD, Beart PM. Lau CL, et al. Among authors: o shea rd. J Cell Physiol. 2012 Mar;227(3):1199-211. doi: 10.1002/jcp.22838. J Cell Physiol. 2012. PMID: 21604263

10

Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis.

O'Shea RD, Lau CL, Zulaziz N, Maclean FL, Nisbet DR, Horne MK, Beart PM. O'Shea RD, et al. Front Neurosci. 2015 Feb 20;9:50. doi: 10.3389/fnins.2015.00050. eCollection 2015. Front Neurosci. 2015. PMID: 25750613 Free PMC article. Review.

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